FB2024_03 , released June 25, 2024
Aberration: Dmel\Df(2L)30A-C
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General Information
Symbol
Df(2L)30A-C
Species
D. melanogaster
Name
FlyBase ID
FBab0001390
Feature type
chromosomal_deletion
Also Known As
Df(2L)30C, Df(2L)30A;C
Computed Breakpoints include

30A3-30A5;30C5

Features within 30A3--30C5
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{wA}4-30
(Lane and Kalderon, 1993)
Mutagen
X ray
(Lane and Kalderon, 1993)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Boube et al., 1997, Harbecke and Lengyel, 1995, Kania et al., 1995, Pauli et al., 1995, Lane and Kalderon, 1993, Schupbach and Wieschaus, 1989)
Breakpoints

30A;30C

(Harbecke and Lengyel, 1995, Pauli et al., 1995, Schupbach and Wieschaus, 1989)

30A3-30A6;30D3-30D4

(Lane and Kalderon, 1993)

29F7-30A1;30C2-30C5

(Kania et al., 1995)

29F7;30C5

(Boube et al., 1997)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

raw << bk1 << Cks30A << l(2)DA2 << bk2 << ms(2)30C

Genetic mapping information
Comments

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

(Marygold et al., 2007)
Comments on Cytology

Ref: Lindsley and Zimm, 1992

(Kania et al., 1995)

Left limit of break 1 from polytene analysis (FBrf0058516) Right limit of break 1 from inclusion of tai (FBrf0067338) Left limit of break 2 from polytene analysis (FBrf0093373) Right limit of break 2 from polytene analysis (FBrf0080145)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
aust
(Gao et al., 2008)
Cks30A
(Pearson et al., 2005, Lane and Kalderon, 1993, Schupbach and Wieschaus, 1989)
gcm
(Kahsai and Cook, 2018, Hosoya et al., 1995, Kania et al., 1995, Lane and Kalderon, 1993)
Gdi
(Kahsai and Cook, 2018, Lane and Kalderon, 1993)
hoip
(Kahsai and Cook, 2018, Spradling et al., 1999, Kania et al., 1995, BDGP Project Members, 1994-1999, Lane and Kalderon, 1993)
l(2)30ABa
(Kahsai and Cook, 2018)
l(2)DA2
(Kahsai and Cook, 2018, Lane and Kalderon, 1993)
l(2)DB1
(Lane and Kalderon, 1993)
l(2)DB2
(Kahsai and Cook, 2018, Lane and Kalderon, 1993)
l(2)DB4
(Kahsai and Cook, 2018, Lane and Kalderon, 1993)
l(2)k05104
(Kahsai and Cook, 2018, Cook, 2014.9.25, BDGP Project Members, 1994-1999)
l(2)k05113a
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
l(2)N7-6
(Kahsai and Cook, 2018, Lane and Kalderon, 1993)
l(2)N7-8
(Kahsai and Cook, 2018, Lane and Kalderon, 1993)
l(2)X
(Lane and Kalderon, 1993)
mat(2)cell-F
(Lane and Kalderon, 1993, Schupbach and Wieschaus, 1989)
mat(2)cell-K
(Schupbach and Wieschaus, 1989)
nAChRα6
(Watson et al., 2010)
numb
(Kahsai and Cook, 2018, Spradling et al., 1999, Wang et al., 1997, Harbecke and Lengyel, 1995, BDGP Project Members, 1994-1999, Lane and Kalderon, 1993)
pelo
(Kahsai and Cook, 2018, Spradling et al., 1999, BDGP Project Members, 1994-1999, Castrillon et al., 1993)
Pka-C1
(Kahsai and Cook, 2018, Spradling et al., 1999, BDGP Project Members, 1994-1999, Lane and Kalderon, 1993, Skoulakis et al., 1993)
scat
(Spradling et al., 1999, BDGP Project Members, 1994-1999, Castrillon et al., 1993)
tai
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
und
(Kahsai and Cook, 2018, Cutforth and Gaul, 1999)
zf30C
(Cook, 2002.3.7)
Partially deleted / disrupted
Molecular Data
Completely deleted
RpS28-like
(Marygold et al., 2007)
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Flies heterozygous for the deletion do not show a Minute bristle phenotype.

    (Marygold et al., 2007)

    The Df(2L)30A-C chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    (Mason et al., 2004)

    Heterozygosity for Df(2L)30A-C results in 2.1% X chromosome nondisjunction and 2.5% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

    (Harris et al., 2003)

    83% of hemisegments show an RP2 to RP2sib cell fate transformation in homozygous embryos.

    (Buescher et al., 1998)

    Intermediate second site non-complementing phenotype with zipEbr and zipmhc-c6.1 : malformed phenotype penetrance 25-75%.

    (Halsell and Kiehart, 1998)

    Shows no maternal enhancement of dpphr4.

    (Nicholls and Gelbart, 1998)

    Shows a dose-sensitive interaction with pbhs.PB.

    (Boube et al., 1997)

    Deficient embryos show a mutant midgut phenotype: midgut primordia do not migrate from terminalia.

    (Bilder and Scott, 1995)

    Midgut primordia do not fuse, but remain at the anterior and posterior of the yolk mass in homozygous embryos. The hindgut is somewhat shorter than normal. The Malpighian tubules bud out but do not elongate.

    (Harbecke and Lengyel, 1995)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)
    Stocks (2)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (8)
    References (46)