FB2024_03 , released June 25, 2024
Aberration: Dmel\Df(2L)sc19-4
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General Information
Symbol
Df(2L)sc19-4
Species
D. melanogaster
Name
Deficiency (2L) scute19
FlyBase ID
FBab0001911
Feature type
chromosomal_deletion
Also Known As
Df(2L)sc19-4
Computed Breakpoints include

25A5;25E5

Features within 25A5--25E5
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Tp(1;2)sc19
Mutagen
X ray
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Rosenberg-Hasson et al., 1996, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Semeshin and Szidonya, 1985)
Breakpoints

25A5-25A6;25E4-25E6

(Semeshin and Szidonya, 1985)

25A4-25A5;25E5-25F1

(Rosenberg-Hasson et al., 1996, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

dp << bk1 << l(2)25Ce << mid << bk2 << E(var)25F

Genetic mapping information
Comments

This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).

(Marygold et al., 2007)
Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0042240) Right limit of break 1 from polytene analysis (FBrf0047784) Left limit of break 2 from inclusion of mid (FBrf0047784) Right limit of break 2 from polytene analysis (citation unavailable)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
cl
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
Hel25E
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Ab
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Ba
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Bb
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Bc
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Bd
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Be
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Bf
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Bg
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Ca
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Cc
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Cd
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Ce
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Cf
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Cg
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Ea
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Ed
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Ee
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
l(2)25Ef
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
Lam
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
mid
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
Msp300
(Rosenberg-Hasson et al., 1996, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
nompC
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
RpL37A
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
slf
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
tkv
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
vri
(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
Partially deleted / disrupted
Molecular Data
Completely deleted
H15
(Leal et al., 2009)
lncRNA:CR31647
(Leal et al., 2009)
mid
(Leal et al., 2009)
mRpL24
(Marygold et al., 2007)
mRpL28
(Marygold et al., 2007)
mRpS2
(Marygold et al., 2007)
RpL37A
(Marygold et al., 2007)
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Embryos trans-heterozygous for Df(2L)sc19-4 and Df(2L)x528 yield an abnormal neuronal cell fate specification phenotype identical to that observed for embryos homozygous for Df(2L)sc19-4.

    (Leal et al., 2009)

    Inferred to overlap with: Df(2L)x528.

    (Leal et al., 2009)
    NOT in combination with other aberrations

    Homozygous Df(2L)sc19-4 embryos exhibit abnormal neuronal cell fate specification in the lateral and medial region of the central nervous system.

    (Leal et al., 2009)

    Flies heterozygous for the deletion show a Minute bristle phenotype.

    (Marygold et al., 2007)

    Sterile and reduced viability.

    (Szidonya and Reuter, 1988)
    Stocks (1)
    Notes on Origin
    Discoverer
     

    Selected for loss of y+.

    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    Df(2L)sc19-4
    (Leal et al., 2009, Mathew et al., 2009, Technau and Roth, 2008)
    Df(2L)sc19-4
    (Rosenberg-Hasson et al., 1996, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Semeshin and Szidonya, 1985)
    Name Synonyms
    Deficiency (2L) scute19
    Secondary FlyBase IDs
      References (15)