FlyBase Aberration Report: Dmel\Df(3R)Espl1

General Information

Symbol

Df(3R)Espl1

Species

D. melanogaster

Name

Deficiency (3R) Enhancer of split

FlyBase ID

FBab0002566

Feature type

chromosomal_deletion

Also Known As

E(spl)^8D06, Df(3R)8D06, Df(3R)E(spl)^8D06, Df(3R)E(spl)8D06

Computed Breakpoints include

96F7;97A3-97A4

Features within 96F7--97A4

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

E(spl)m8-HLH¹

(Shepard et al., 1989)

Mutagen

X ray

ethyl methanesulfonate

(Preiss et al., 1988, Ziemer et al., 1988, Knust et al., 1987, Tearle and Nusslein-Volhard, 1987)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Shepard et al., 1989)

Breakpoints

96F;97A3-97A4

(Shepard et al., 1989)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

M285 << bk1 << E(spl) << gro << bk2

Genetic mapping information

Comments

Comments on Cytology

Limits of break 1 from polytene analysis (citation unavailable) Limits of break 2 from polytene analysis (FBrf0049904)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

E(spl)m8-HLH

(Bate et al., 1993, Bodmer et al., 1993, Tearle and Nusslein-Volhard, 1987)

Exo84

(Giansanti et al., 2004)

gro

(Bodmer et al., 1993)

yeti-MBT

(Riede, 1996)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

M285

(Go and Artavanis-Tsakonas, 1998)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location

Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

Heterozygotes raised at 29^oC have extra vein material in the posterior cell of the wing, with a penetrance of less than 20%.

(Ahmed et al., 2003)

In Df(3R)Espl1/Tp(3;3)Vno flies ectopic macrochaetae are often observed on the scutellum and in the row of dorso-central bristles.

(Nagel et al., 2000)

No significant effect on the sca^MSKF mutant phenotype.

(Hu et al., 1995)

Embryos exhibit few, if any, fused muscles. The unfused, birefringent fibres, have a random pattern of fine fibres apparently radiating out from small fragments of dorsal cuticle.

(Bate et al., 1993)

Hyperplasia of replicating sensory precursors: due to an increased number of ectodermal cells being recruited as sensory precursor cells.

(Bodmer et al., 1993)

Homozygous embryos have a extreme neurogenic phenotype: minuscule patch of dorsoposterior cuticle or two patches of posterior lateral cuticle due to failure in dorsal closure.

(Delidakis et al., 1991)

Strong phenotypic reversion: 250--350 facets per eye. Severe embryonic phenotype: loss of ventral, lateral and majority of dorsal cuticle. Viable when heterozygous with a Dl allele.

(Shepard et al., 1989)

Embryonic lethal, extreme neurogenic phenotype.

(Preiss et al., 1988)

Lethal in combination with gro and E(spl)¹. Homozygotes have extreme neural hyperplasia and suppress the N^spl-1 phenotype.

(Ziemer et al., 1988)

Embryonic lethal affecting epidermal development.

(Knust et al., 1987)

Stocks (0)

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (10)

Reported As

Symbol Synonym

Df(3R)8D06

(Riede, 2001, Riede, 1996, Jennings et al., 1994, Delidakis et al., 1991, Preiss et al., 1988)

Df(3R)^8D06

(Nagel et al., 2000)

Df(3R)E(spl)1

(Bate et al., 1993)

Df(3R)E(spl)8D06

(Hartenstein et al., 1996, Shepard et al., 1989)

Df(3R)E(spl)^8D06

(Tepass and Hartenstein, 1995, Bodmer et al., 1993)

Df(3R)Espl-8D

(Tearle and Nusslein-Volhard, 1987)

Df(3R)Espl1

(Giansanti et al., 2015, Casso et al., 2011)

E(spl)^8D06

(Ahmed et al., 2003, Helms et al., 1999, Go and Artavanis-Tsakonas, 1998, Long et al., 1996, Hu et al., 1995, Rhyu et al., 1994, Bate et al., 1993, Hartenstein et al., 1992, Skeath and Carroll, 1992, Ziemer et al., 1988, Knust et al., 1987)

E(spl)^8D

(Tearle and Nusslein-Volhard, 1987)

Name Synonyms

Deficiency (3R) Enhancer of split

Secondary FlyBase IDs

FBal0029655
FBal0044764

References (27)

Report Sections

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