FlyBase Aberration Report: Dmel\In(2LR)O

General Information

Symbol

In(2LR)O

Species

D. melanogaster

Name

Inversion (2LR) of Oster

FlyBase ID

FBab0004786

Feature type

chromosomal_inversion

Also Known As

CyO

Computed Breakpoints include

30E-30F;50C10-50D1

Sequence coordinates

2L:9,805,567..9,805,567 (In(2LR)O:bk1)

(Miller et al., 2018)

2R:14,067,771..14,067,771 (In(2LR)O:bk2)

(Miller et al., 2018)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

2Lt - 22D1 | 33F5 - 30F | 50D1 - 58A4 | 42A2 - 34A1 | 22D2 - 30E | 50C10 - 42A3 | 58B1 - 2Rt

Progenitor

Mutagen

(Bourgouin et al., 1992)

Class of aberration (relative to wild type)

chromosomal_inversion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_inversion

(Yedvobnick et al., 1988)

Breakpoints

30E-30F;50C-50D

(Yedvobnick et al., 1988)

30E2-30F6;50C10-50D1;[30E2-30F6];[50C10-50D1];

(Watson et al., 2010)

Causes alleles

nAChRα6^O

(Miller et al., 2018, Watson et al., 2010, Perry et al., 2007)

Prosap^O

(Miller et al., 2018)

Carries alleles

Transposon Insertions

pogo{}nAChRα6^O

(Perry et al., 2007)

Formalized genetic data

Genetic mapping information

Comments

The 5' (distal) end of this breakpoint corresponds to 2L:9 ,805,567 and the 3' (proximal) end corresponds to 2L:9 ,805,575 (release 6 coordinates), meaning that 7bp of genomic sequence is deleted at this breakpoint.

(Miller et al., 2018)

The 5' (proximal) end of this breakpoint corresponds to 2R:14 ,067,771 and the 3' (distal) end corresponds to 2R:14 ,067,782 (release 6 coordinates), meaning that 10bp of genomic sequence is deleted at this breakpoint.

(Miller et al., 2018)

One of the inversions of the In(2LR)O chromosome fuses nAcRα-30D sequence from exon 8b (cytologically located at 30D) to the 5' end of Prosap (cytologically located at 50C). An internally deleted remnant of a pogo transposable element is also present on the nAcRα-30D side of the inversion.

(Perry et al., 2007)

Breakpoint(s) molecularly mapped

(Yedvobnick et al., 1988)

50C-D breakpoint distal to mam; between coordinates +25 and +29 on the chromosome walk including mam (Yedvobnick, Smoller, Young and Mills, 1988, Genetics 118: 483-97).

Comments on Cytology

Breakpoint molecularly mapped.

(Yedvobnick et al., 1988)

Limits of break 1 from polytene analysis (FBrf0048222) Limits of break 2 from polytene analysis (citation unavailable)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

nAChRα6

(Miller et al., 2018, Perry et al., 2007)

Prosap

(Miller et al., 2018)

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location

Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

Stocks (10)

Kyoto

107652

Tp(2;3)Me/In(2LR)O, In(2LR)Gla, Duox^Cy wg^Gla-1

108813

Df(2R)XTED1/In(2LR)O, In(2LR)Gla, Duox^Cy wg^Gla-1

101519

Dp(2;2)Cam1 / In(2LR)O, Duox^Cy dpy^lv1 pr¹ cn¹ bw¹

108964

In(2LR)O, In(2LR)Gla, Duox^Cy wg^Gla-1/Dp(?;2)bw^D, S¹ bw^D

101524

Dp(2;2)Cam16, b¹ bw¹ / In(2LR)O, Duox^Cy dpy^lv1 pr¹ cn²

101520

Dp(2;2)Cam2, speck¹ / In(2LR)O, Duox^Cy dpy^lv1 pr¹ cn¹ bw¹

101521

Dp(2;2)Cam4, Dp(1;2)TE23CD, vg¹ / In(2LR)O, Duox^Cy dpy^lv1 pr¹ cn¹ bw¹

101522

Dp(2;2)Cam3, bw¹ speck¹ / In(2LR)O, Duox^Cy dpy^lv1 pr¹ cn¹ bw¹

101523

Dp(2;2)Cam12, Dp(1;2)TE23CD, net¹ dpp^d-ho / In(2LR)O, Duox^Cy dpy^lv1 pr¹ cn²

101353

cos⁵ cn¹ bw¹ speck¹ / In(2LR)O, Df(2R)cn-S6, Duox^Cy dpy^lv1 pr¹ cn^-

Notes on Origin

Discoverer

Oster.

Induced on: In(2L)Cy In(2R)Cy Cy dp^lvI pr cn².

Balancer / Genotype Variants of the Aberration

CyO

(Ghavi-Helm et al., 2019, Miller et al., 2019, Miller et al., 2018, FlyBase Curators, 2006-)

CyO-2XGMRrpr

(FlyBase Curators, 2006-)

CyO-2xTb-RFP

(Pina and Pignoni, 2012)

CyO-7.1

(FlyBase Curators, 2006-)

CyO-19

(FlyBase Curators, 2006-)

CyO-23

(FlyBase Curators, 2006-)

CyO-30

(FlyBase Curators, 2006-)

CyO-37

(FlyBase Curators, 2006-)

CyO-208

(FlyBase Curators, 2006-)

CyO-217-038

(FlyBase Curators, 2006-)

CyO-238-022

(FlyBase Curators, 2006-)

CyO-238-048

(FlyBase Curators, 2006-)

CyO-276

(FlyBase Curators, 2006-)

CyO-402

(FlyBase Curators, 2006-)

CyO-509

(FlyBase Curators, 2006-)

CyO-520-009

(FlyBase Curators, 2006-)

CyO-520-021

(FlyBase Curators, 2006-)

CyO^T8LZ

(FlyBase Curators, 2006-)

CyO-A4

(FlyBase Curators, 2006-)

CyO-A22

(Perrimon et al., 1991)

CyO-A32

(FlyBase Curators, 2006-)

CyO-A66

(FlyBase Curators, 2006-)

CyO-A79

(FlyBase Curators, 2006-)

CyO-A80

(Perrimon et al., 1991)

CyO-A103

(FlyBase Curators, 2006-)

CyO-A130

(FlyBase Curators, 2006-)

CyO-A176

(FlyBase Curators, 2006-)

CyO-A203

(FlyBase Curators, 2006-)

CyO-A217

(FlyBase Curators, 2006-)

CyO-A336

(FlyBase Curators, 2006-)

CyO-A350

(FlyBase Curators, 2006-)

CyO-A405

(FlyBase Curators, 2006-)

CyO-A480

(FlyBase Curators, 2006-)

CyO-A495

(FlyBase Curators, 2006-)

CyO-A507

(FlyBase Curators, 2006-)

CyO-B26.2-4.2

(FlyBase Curators, 2006-)

CyO-B26.2-16.1

(FlyBase Curators, 2006-)

CyO-B26.2-33.1

(FlyBase Curators, 2006-)

CyO-B26.2-36.1

(FlyBase Curators, 2006-)

CyO-B39

(FlyBase Curators, 2006-)

CyO-BG00000

(FlyBase Curators, 2006-)

CyO-brk

(FlyBase Curators, 2006-)

CyO-bw

(FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)

CyO-CC2

(FlyBase Curators, 2006-)

CyO-CCAG

(FlyBase Curators, 2006-)

CyO-CG

(Paladi and Tepass, 2004)

CyO-cl⁴

(FlyBase Curators, 2006-)

CyO-cn⁺

(FlyBase Curators, 2006-)

CyO-CR2

(FlyBase Curators, 2006-)

CyO-CTG

(FlyBase Curators, 2006-)

CyO-CZ

(FlyBase Curators, 2006-)

CyO-dpc

(FlyBase Curators, 2006-)

CyO-DTS100

(FlyBase Curators, 2006-)

CyO-DTS486

(FlyBase Curators, 2006-)

CyO-DTS513

(FlyBase Curators, 2006-)

CyO-E(var)2-1

(Lerach et al., 2006)

CyO-EY00000

(FlyBase Curators, 2006-)

CyO-FRT

(FlyBase Curators, 2006-)

CyO-ftz-lacZ

(FlyBase Curators, 2006-)

CyO-GCY

(FlyBase Curators, 2006-)

CyO-GFP

(FlyBase Curators, 2006-)

CyO-GMRargos

(FlyBase Curators, 2006-)

CyO-GS046

(FlyBase Curators, 2006-)

CyO-hb-β-gal

(FlyBase Curators, 2006-)

CyO-HoP2.1

(FlyBase Curators, 2006-)

CyO-HoP3

(FlyBase Curators, 2006-)

CyO-HShid

(FlyBase Curators, 2006-)

CyO-Hsp70-PBac\T.w⁺

(FlyBase Curators, 2006-)

CyO-Hsp70-PBac\T.w^-

(FlyBase Curators, 2006-)

(Sun et al., 2012)

(Sun et al., 2012)

(Sun et al., 2012)

(Sun et al., 2012)

(Therrien et al., 2000)

CyO-Mhc-lacZ

(FlyBase Curators, 2006-)

CyO-MiT2.4

(FlyBase Curators, 2006-)

CyO-nec^JR

(FlyBase Curators, 2006-)

CyO-numb^k09918

(FlyBase Curators, 2006-)

CyO-P20

(FlyBase Curators, 2006-)

CyO-P{Cre^hsy}SH2b

(Siegal and Hartl, 2000)

CyO-P{Crew}

(FlyBase Curators, 2006-)

CyO-P{dam⁺.phy705}11

(FlyBase Curators, 2006-)

CyO-P{dam⁺.phy705}12

(FlyBase Curators, 2006-)

CyO-P{dam⁺.phy705}34

(FlyBase Curators, 2006-)

CyO-P{Dfd-EYFP.w^BmC}2

(FlyBase Curators, 2006-, Le et al., 2006)

CyO-P{Dfd-EYFP}2

(FlyBase Curators, 2006-, Le et al., 2006)

CyO-P{Dfd-GMR-nvYFP}2

(Beitel, 2007.4.20)

CyO-P{en1}wg^en11

(FlyBase Curators, 2006-)

CyO-P{EPg}4-38

(FlyBase Curators, 2006-)

CyO-P{ftz/lacC}USC1

(FlyBase Curators, 2006-)

CyO-P{ftz-lacZ.w⁺}

(FlyBase Curators, 2006-)

CyO-P{GAL4-Hsp70.PB.w^mC.mut}MP

(FlyBase Curators, 2006-)

CyO-P{GMR-MAPT.V337M}2

(Jackson, 2013.9.11)

CyO-P{GMR-p21.Ex}2

(FlyBase Curators, 2006-)

CyO-P{GMR-sina.N}2

(Richardson, 2010.5.17)

CyO-P{HBL1}1

(FlyBase Curators, 2006-)

CyO-P{HBL1}2

(FlyBase Curators, 2006-)

CyO-P{hsH\T-2}1

(FlyBase Curators, 2006-)

CyO-P{hsH\T-2}2

(FlyBase Curators, 2006-)

CyO-P{lacW}29D

(Hoshizaki et al., 1994)

CyO-P{lacW}B

(FlyBase Curators, 2006-)

CyO-P{lacW}S

(FlyBase Curators, 2006-)

CyO-P{ovoD1-18}131

(FlyBase Curators, 2006-)

CyO-P{sChFP}2

(Abreu-Blanco et al., 2012, Parkhurst, 2011.4.14)

CyO-P{sE-raf^torY9}475

(FlyBase Curators, 2006-)

CyO-P{sev-N^act}2

(Fortini, 2015.8.26)

CyO-P{SUPor-P}RR1

(FlyBase Curators, 2006-, Cook, 2004.12.14)

CyO-P{tub-QS.P.w-}L1

(Riabinina and Potter, 2013.10.1)

CyO-P{tub-QS.P}L1

(Potter and Luo, 2010.5.24)

CyO-P{UAS.RMCE.w⁺}3A

(Matinyan et al., 2021)

CyO-P{UAS.RMCE.w⁺}4A

(Matinyan et al., 2021)

CyO-P{UAS-rpr.C}2

(Sekelsky, 2013.10.1)

CyO-P{w^en.6}16C

(Kassis, 1994)

CyO-P{Wee-P.ph0}2

(Roegiers, 2012.2.10, Casso, 2007.11.4)

CyO-pAct-GFP

(FlyBase Curators, 2006-)

CyO-PBac{Delta2-3.Exel}2

(FlyBase Curators, 2006-)

CyO-PBac{lexA::GAD.G4HACK}42A13

(Chang et al., 2022)

CyO-PBac{lexA::GAD.G4HACKy}42A13

(Rankin et al., 2024)

CyO-PBac{y⁺-attP-9A}42A13

(Chang et al., 2022)

CyO-pcb

(FlyBase Curators, 2006-)

CyO-pk^pk-sple-46

(FlyBase Curators, 2006-)

CyO-pk^pk-sple-48

(FlyBase Curators, 2006-)

CyO-Rb

(FlyBase Curators, 2006-)

CyO-Rcb

(FlyBase Curators, 2006-)

CyO-Rcb(P)

(FlyBase Curators, 2006-)

CyO-Rs(P)

(FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)

CyO-Sbw

(Lattao et al., 2011, FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)

CyO-SCY

(FlyBase Curators, 2006-)

CyO-sp

(FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2000.1.21)

CyO-SX4-2-10

(Kim et al., 2023)

CyO-TbA

(Lattao et al., 2011)

CyO-TbB

(Lattao et al., 2011)

CyO-TbC

(Lattao et al., 2011)

CyO-Thb8

(FlyBase Curators, 2006-)

CyO-tub-Gal80

(FlyBase Curators, 2006-)

CyO-Tub-PBac\T.w⁺

(FlyBase Curators, 2006-)

CyO-Tub-PBac\T.w^-

(FlyBase Curators, 2006-)

CyO-UW14

(FlyBase Curators, 2006-)

CyO-vAa

(FlyBase Curators, 2006-)

CyO-vAb

(FlyBase Curators, 2006-)

CyO-vAc

(FlyBase Curators, 2006-)

CyO-vAe

(FlyBase Curators, 2006-)

CyO-vAg

(FlyBase Curators, 2006-)

CyO-vDAa

(FlyBase Curators, 2006-)

CyO-vGa

(FlyBase Curators, 2006-)

CyO-vKa

(FlyBase Curators, 2006-)

CyO-vOa

(FlyBase Curators, 2006-)

CyO-vOb

(FlyBase Curators, 2006-)

CyO-vPa

(FlyBase Curators, 2006-)

CyO-vSa

(FlyBase Curators, 2006-)

CyO-vSb

(Schnorrer, 2009.3.22)

CyO-vWa

(FlyBase Curators, 2006-)

CyO-vWb

(FlyBase Curators, 2006-)

CyO-y⁺

(FlyBase Curators, 2006-, Mardahl et al., 1993)

CyO-Δ46G

(FlyBase Curators, 2006-)

CyO-β-actin

(FlyBase Curators, 2006-)

CyO-βE3

(FlyBase Curators, 2006-)

Separable Components

Other Comments

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

CyO

(Schnorrer, 2009.3.22, Perry et al., 2007, Morrissey et al., 1991, Smoller et al., 1990, Yedvobnick et al., 1988, Falke and Wright, 1972)

In(2LR) CyO

(Avila et al., 2011)

In(2LR)CyO

In(2LR)O

(Miller et al., 2018, Watson et al., 2010)

InsO5

Name Synonyms

Inversion (2LR) of Oster

Secondary FlyBase IDs

FBab0024657
FBab0026201

References (239)

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