FlyBase Aberration Report: Dmel\Df(2R)520

FB2024_03 , released June 25, 2024

FB2024_03 , released June 25, 2024

Aberration: Dmel\Df(2R)520

General Information

Symbol

Df(2R)520

Species

D. melanogaster

Name

FlyBase ID

FBab0023586

Feature type

chromosomal_deletion

Also Known As

Df(2R)P520

Computed Breakpoints include

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

(O'Brien et al., 1994)

Mutagen

Delta2-3 transposase

(O'Brien et al., 1994)

Class of aberration (relative to wild type)

chromosomal_deletion

Class of aberration (relative to progenitor)

Breakpoints

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

Genetic mapping information

Comments

Comments on Cytology

Distal breakpoint is located within Df(2R)eve.

(O'Brien et al., 1994)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

(O'Brien et al., 1994)

(O'Brien et al., 1994)

(Bour et al., 1995)

(O'Brien et al., 1994)

(BDGP Project Members, 1994-1999)

(Qian et al., 2005, Goldstein et al., 2001, Prokop et al., 1996, Bour et al., 1995, Bour et al., 1995)

(Cenci et al., 2015)

(O'Brien et al., 1994)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

(Goldstein et al., 2001)

(Goldstein et al., 2001, Bour et al., 1995)

(Goldstein et al., 2001, Bour et al., 1995)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(Goldstein et al., 2001, Bour et al., 1995)

(Goldstein et al., 2001, Bour et al., 1995)

(Goldstein et al., 2001, Bour et al., 1995)

(Goldstein et al., 2001, Bour et al., 1995)

(Goldstein et al., 2001, Bour et al., 1995)

(Goldstein et al., 2001, Bour et al., 1995)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(Goldstein et al., 2001)

(BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

(Goldstein et al., 2001)

(Goldstein et al., 2001, Bour et al., 1995)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location

Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

Muscle founder cells do not fuse with surrounding myocytes in mutant embryos.

(Su et al., 1999)

Muscle founder cells of Mef2^22-21/Df(2R)520 transheterozygotes never differentiate to form mononucleate muscles. Con, vg or Fas3-expressing founder cells show that target recognition takes place and motoneurons that establish contact are always attracted to the correct founder cells. Myoblast fusion and Mhc and βTub60D expression are severely affected, thus general features of differentiated muscle are deranged or missing. Normal neuromuscular junctions are wholly absent.

(Prokop et al., 1996)

Stocks (0)

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Df(2R)520

Df(2R)P520

(Landgraf et al., 1999, Lin et al., 1996, Prokop et al., 1996, Bour et al., 1995)

Dmef2^P520

(Su et al., 1999)

Mef2^P520

(Han et al., 2002)

p520

(Cenci et al., 2015)

peo^Δ520

(Cenci et al., 2015)

Name Synonyms

Secondary FlyBase IDs

FBab0022048

References (12)

Report Sections