FB2024_03 , released June 25, 2024
Aberration: Dmel\Df(2L)Pi3K21B-A
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General Information
Symbol
Df(2L)Pi3K21B-A
Species
D. melanogaster
Name
FlyBase ID
FBab0028843
Feature type
chromosomal_deletion
Also Known As
p60A, Df(2L)p60A, plc21Cp60A
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{lacW}Plc21Ck31911
(Weinkove et al., 1999)
Mutagen
P-element activity
(Weinkove et al., 1999)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
Breakpoints

[];[]

(Weinkove et al., 1999)
Causes alleles
Plc21CA
(Weinkove et al., 1999)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Plc21C
(Weinkove et al., 1999)
Stip1
(Weinkove et al., 1999)
U2af38
(Weinkove et al., 1999)
Partially deleted / disrupted
Molecular Data
Completely deleted
Pi3K21B
(Weinkove et al., 1999)
Stip1
(Weinkove et al., 1999)
U2af38
(Weinkove et al., 1999)
Partially deleted
Plc21C
(Weinkove et al., 1999)
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Complements Df(2L)al.

    (Weinkove et al., 1999)
    NOT in combination with other aberrations

    Df(2L)Pi3K21B-A heterozygotes do not show decreased avoidance to CO2, as compared to controls.

    (Badsha et al., 2012)

    Df(2L)Pi3K21B-A/Df(2L)Pi3K21B-B, P{U2af38.gR10} mutants (null for Pi3K21B) stop growing normally early in the third larval instar. Though they continue to move and feed for approximately 20 days they grow very slowly. Larvae are transparent, have small imaginal discs and have reduced fat body. Nervous system, trachea and gut appear normal. Some form pupal cases but show no indication of pupal development. Mutant clones in the eye reveal that Pi3K21B is autonomously required for adult cells to reach their normal size.

    (Weinkove et al., 1999)
    Stocks (1)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    18kb deletion extending distally from the site of insertion of the P{lacW} in the progenitor chromosome.

    (Weinkove et al., 1999)
    Synonyms and Secondary IDs (7)
    Reported As
    Symbol Synonym
    Df(2L)Pi3K21B-A
    (Fernandes and Rao, 2011)
    Df(2L)p60A
    (Badsha et al., 2012, Kain et al., 2009, Kain et al., 2008)
    Pi3K21BA
    p60A
    (Orme et al., 2006, Coelho et al., 2005, Clancy et al., 2001, Jin et al., 2001, Weinkove et al., 1999)
    p60A
    (Miron et al., 2001)
    plc21Cp60A
    (Badsha et al., 2012)
    plc21cp60A
    (Kain et al., 2009)
    Name Synonyms
    Secondary FlyBase IDs
    • FBal0124096
    References (11)