FB2024_03 , released June 25, 2024
Aberration: Dmel\Df(3L)Exel6128
Open Close
General Information
Symbol
Df(3L)Exel6128
Species
D. melanogaster
Name
FlyBase ID
FBab0038148
Feature type
Computed Breakpoints include

[72D9-72D9];[72D10-72D10];

Genomic Maps
Sequence coordinates
3L:16,129,654..16,129,654 (Df(3L)Exel6128:bk1)
3L:16,217,328..16,217,328 (Df(3L)Exel6128:bk2)
Member of large scale dataset(s)
Dfs_Exelixis_set1

A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial set of 519 isogenic deletions provides 56% genome coverage.

The current Exelixis collection at the Bloomington Stock Center differs from the original described in FBrf0175003 : a significant number were shown not to carry a deletion and have been removed from the collection; a number of stocks have been lost; a number of additional deletions are included that were generated after publication.

Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Breakpoint from FlyBase's release 5 sequence location of progenitor insertion.

Comments on Cytology
Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
Phenotypic Data
In combination with other aberrations

Df(3L)Exel6128/Df(3L)BSC559 flies or Df(3L)Exel6128/Df(3L)BSC560 flies, derived from heterozygous parents, are viable, fertile and have no discernable phenotypes despite the fact these deficiencies overlap by 55 kb of genomic DNA. However, when these flies are inbred for several generations, their progeny often have thin bristles and etched abdominal tergites. These phenotypes are not rescued by either of two paternally inherited duplications (Ts(YSt;3Lt)ST1 or Dp(3;Y)L131-D3), indicating that the phenotypes are not caused by deleting the 55 kb genomic region, but by a maternal-effect mutation somewhere else in the genome.

Df(3L)Exel6128/Df(3L)st4 flies are viable, despite the fact these deficiencies overlap.

NOT in combination with other aberrations

elg1MI08386/Df(3L)Exel6128 females display the same underreplicated nurse cell phenotype characteristic for elg1MI08386 mutants and are also sterile.

Stocks (1)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (9)