FB2024_03 , released June 25, 2024
Aberration: Dmel\Df(3L)Brd-C1
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General Information
Symbol
Df(3L)Brd-C1
Species
D. melanogaster
Name
FlyBase ID
FBab0045446
Feature type
chromosomal_deletion
Also Known As
Df(3)Brd-C1
Computed Breakpoints include
Features within 71A2--71A4 (Estimated cytology)
Genomic Maps
Sequence coordinates
3L:14,940,015..14,940,015 (Df(3L)Brd-C1:bk1)
(Bardin and Schweisguth, 2006)
3L:14,977,843..14,977,843 (Df(3L)Brd-C1:bk2)
(Bardin and Schweisguth, 2006)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
PBac{WH}DCX-EMAPf02655
(Bardin and Schweisguth, 2006)
P{XP}d02180
(Bardin and Schweisguth, 2006)
Mutagen
FLPase
(Bardin and Schweisguth, 2006)
Class of aberration (relative to wild type)
chromosomal_deletion
(Bardin and Schweisguth, 2006)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Bardin and Schweisguth, 2006)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

A 38Kb deletion generated by 'FLPase' induced recombination between the insertions P{XP}d02180 and PBac{WH}CG42247f02655.

(Bardin and Schweisguth, 2006)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
BobA
(Chanet et al., 2009)
BobB
(Chanet et al., 2009)
Brd
(Chanet et al., 2009)
Ocho
(Chanet et al., 2009)
Tom
(Chanet et al., 2009)
Partially deleted
DCX-EMAP
(Chanet et al., 2009, Bardin and Schweisguth, 2006)
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
CG3349
(Chanet et al., 2009)
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
Phenotypic Data
In combination with other aberrations

Stage 9/10 Df(3L)Brd-C1/Df(3R)E(spl)δ-6 transheterozygous embryos display loss of apical-basal cell polarity and of epithelial integrity; both these are rescued by sdtΔ3-GFP but not by sdtGFP3.

(Perez-Mockus et al., 2017)

39% of embryos homozygous for the Df(3L)Brd-C1 and Df(3R)E(spl)δ-6 deletions and carrying one copy of Dp(3;2)E(spl)δ-8 fail to hatch and only 2% reach pupal stages.

(Chanet et al., 2009)

DCX-EMAPtCa does not rescue the lethality of Df(3L)Brd-C1.

(Chanet et al., 2009)

Animals homozygous for the Df(3L)Brd-C1 and Df(3R)E(spl)δ-6 deletions and carrying one copy of Dp(3;2)E(spl)δ-8Δα46 are 100% embryonic lethal.

(Chanet et al., 2009)

The lethality of Df(3L)Brd-C1 is partially rescued by Dp(3;2)Brd-C; 20% of embryos develop into adult flies that are fertile.

(Chanet et al., 2009)
NOT in combination with other aberrations

60% of mutant animals die as embryos, and only 6% reach adulthood.

Homozygous clones in the notum do not perturb bristle development.

(Chanet et al., 2009)
Stocks (0)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Df(3)Brd-C1
(Caygill and Brand, 2017, Perez-Mockus et al., 2017, Chanet et al., 2009)
Df(3L)Brd-C1
(Bardin and Schweisguth, 2006)
Name Synonyms
Secondary FlyBase IDs
    References (4)