FB2024_03 , released June 25, 2024
Allele: Dmel\cn2
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General Information
Symbol
Dmel\cn2
Species
D. melanogaster
Name
FlyBase ID
FBal0001732
Feature type
allele
Associated gene
Dmel\cn
Associated Insertion(s)
roo{}cn-2.1
roo{}cn-2.2
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

Mutagen
spontaneous
(Warren et al., 1996)
Progenitor genotype
Associated Insertion(s)
roo{}cn-2.1
roo{}cn-2.2
Cytology
Description

Associated with two roo insertions: one with a 70-nt target site duplication (TSD) of 2R:7 ,784,487-7,784,556 that includes the 1st intron and 2nd exon of cn, and the other in the 1st intron of cn with a 6-nt TSD of 2R:7 ,784,682-7,784,687.

(Miller et al., 2018)

8kb DNA insertion.

(Warren et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Malpighian tubes of cn2/cn1 pale yellow.

      (Brehme and Demerec, 1942)

      Eye colour: brighter than wild-type. Eye colour: bright scarlet; darkens with age, with cn1. Ocellus colour: pale. Ocellus colour: colourless, with cn1. RK2.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (266)
      Notes on Origin
      Discoverer

      L. Ward, 1921.

      Induced on: In(2R)Cy.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      cn2
      (Miller et al., 2018)
      Name Synonyms
      Secondary FlyBase IDs
        References (16)