FB2024_03 , released June 25, 2024
Allele: Dmel\cos7
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General Information
Symbol
Dmel\cos7
Species
D. melanogaster
Name
FlyBase ID
FBal0001777
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Adult escapers display a strong cos wing phenotype.

Hemizygous lethal but homozygous viable. In homozygotes, wing duplications are evident. cos2/cos7 and cos6/cos7 flies display local pattern duplications on the anterior margin of the wings and halteres. cos6/cos7 flies are sick and sterile. Embryos derived from mutant germ line clones have normal segmentation but a deletion phenotype in each segment such that virtually the entire denticle belt is deleted, leaving only one or two of the anterior-most rows of denticles. The width of the denticle belts is also reduced. A few embryos show an anterior open phenotype.

class II allele

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Grau & Simpson.

Comments
Comments

Allelic series: cos3 >= cos2 >= cos1 = cos4 = cos5 >= cos6 >= cos7.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)