FB2024_03 , released June 25, 2024
Allele: Dmel\Pi4KIIIα13
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General Information
Symbol
Dmel\Pi4KIIIα13
Species
D. melanogaster
Name
FlyBase ID
FBal0006877
Feature type
allele
Associated gene
Dmel\Pi4KIIIα
Associated Insertion(s)
Carried in Construct
Also Known As
l(1)zw2c21, zw2c21
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
Progenitor genotype
Cytology

Polytene chromosomes normal (Judd).

Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous germline clones were viable but yield no eggs.

      (Garcia-Bellido and Robbins, 1983)

      Lethality occurs during embryonic and larval stages. Some die within the egg membranes, others hatch but do not grow, they die within 24 hours after hatching. Mosaic analysis demonstrates mutant phenotype is non-autonomous.

      (Shannon et al., 1972)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Judd, 21 Mar. 1962.

      Comments
      Comments

      Shows a maternal-zygotic interaction, demonstrated in males carrying mutant allele from heterozygous mother and variegating allele in the paternally derived Dp(1;4)mg.

      (Robbins, 1983)

      Maternal germline clonal analysis demonstrates cell lethality in homozygous clones.

      (Perrimon et al., 1989)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      PI4KIIIα13
      Pi4KIIIα13
      l(1)3Ah13
      l(1)zw2c21
      (Garcia-Bellido and Robbins, 1983, Judd et al., 1972, Shannon et al., 1972)
      zw-262c21
      (Liu and Lim, 1975)
      zw2c21
      (Perrimon et al., 1989, Robbins, 1983)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)