FB2024_03 , released June 25, 2024
Allele: Dmel\l(1)3Bb4
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General Information
Symbol
Dmel\l(1)3Bb4
Species
D. melanogaster
Name
FlyBase ID
FBal0006960
Feature type
allele
Associated gene
l(1)3Bb
Associated Insertion(s)
Carried in Construct
Also Known As
l(1)zw6e5
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      First instar larvae do not grow. Mosaic analysis demonstrates mutant phenotype is non-autonomous, clones survive as sectors of mutant tissue only in the abdomen. Individuals survive when Dp(1;4)wm65g or Dp(1;3)wm49a is present (at 25oC but not 18oC). Surviving males are phenotypically normal and fertile.

      (Shannon et al., 1972)

      L1 larval lethal; no growth. survive as XY but not as X0 males in presence of either Dp(1;4)wm65g or Dp(1;3)wm49a. Survive as gynandromorphs when only tergites and occasionally wing tissue mutant; mutant tissue etched, lacks bristles and deformed in the case of wing tissue (Shannon, Kaufman, Shen and Judd, 1972). viable in epidermal clones.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Judd, 5 March 1963.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      63e5
      (Thierry-Mieg, 1982)
      l(1)3Bb4
      (Tan et al., 2014)
      l(1)zw6e5
      (Garcia-Bellido and Robbins, 1983, Judd et al., 1972, Shannon et al., 1972)
      zw-663e5
      (Liu and Lim, 1975)
      zw6e5
      (Robbins, 1983)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)