FB2024_03 , released June 25, 2024
Allele: Dmel\kuzk11804
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General Information
Symbol
Dmel\kuzk11804
Species
D. melanogaster
Name
FlyBase ID
FBal0008398
Feature type
allele
Associated gene
Dmel\kuz
Associated Insertion(s)
P{lacW}kuzk11804
Carried in Construct
Also Known As
l(2)k11804
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Rooke et al., 1996)
Mutagen
P-element activity
(Roch et al., 1998, Sotillos et al., 1997, Rooke et al., 1996)
Progenitor genotype
Associated Insertion(s)
P{lacW}kuzk11804
Cytology
Description

Insertion of a P{lacW} element within untranslated leader sequences.

(Sotillos et al., 1997)

P{lacW} insertion within either the first intron or the first exon.

(Rooke et al., 1996)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethality occurs during third instar larval or pupal stages. Mutants exhibit visible disc abnormalities. In tergites, clones with normal size and frequency are recovered. Clones cannot be recovered in the wing disc.

      (Roch et al., 1998)

      Homozygous larvae have imaginal discs similar in size and shape to those of kuzk01405 homozygous larvae. Homozygous clones induced in the thorax at 48-72 hours after egg laying produce tufts of microchaetae and areas of naked cuticle.

      (Sotillos et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      I. Kiss.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      118/4
      (Roch et al., 1998)
      kuzk11804
      l(2)k11804
      (Sotillos et al., 1997, Rooke et al., 1996)
      l(2)k11804k11804
      Name Synonyms
      Secondary FlyBase IDs
        References (7)