FB2024_03 , released June 25, 2024
Allele: Dmel\Catsupcs2
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General Information
Symbol
Dmel\Catsupcs2
Species
D. melanogaster
Name
FlyBase ID
FBal0008646
Feature type
allele
Associated gene
Dmel\Catsup
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Schupbach and Wieschaus, 1991)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Shows extremely reduced viability at 22oC and complete lethality at 18oC. Hemizygous escaper females are completely sterile. 5-10% of Catsupcs2 heterozygous adults have melanotic pseudotumours. Hemizygous females show an abnormal retention of eggs.

      (Stathakis et al., 1999)

      Eggs are tiny due to a failure to transport nurse cell content into the oocyte.

      (Schupbach and Wieschaus, 1991)

      Homozygous females lay tiny eggs which remain unfertilized.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Schupbach.

      Comments
      Comments

      Renamed from fs3 to cs2 upon discovery of cold-sensitive phenotype.

      (Stathakis et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Catsupcs2
      (Roshina and Pasyukova, 2007)
      Catsupfs3
      QT50
      (Schupbach and Wieschaus, 1991)
      l(2)37Bcfs3
      l(2)QT50
      Name Synonyms
      Secondary FlyBase IDs
        References (4)