FB2024_03 , released June 25, 2024
Allele: Dmel\mus101D2
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General Information
Symbol
Dmel\mus101D2
Species
D. melanogaster
Name
FlyBase ID
FBal0012590
Feature type
allele
Associated gene
Dmel\mus101
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description

Partial deletion of mus101 coding sequences (c.3168-3659del, p.K1056fs).

(Kondo and Perrimon, 2011)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      mus101D2 mutants have a similar frequency of single-strand annealing repair (SSA) compared to controls in a P{wIw.FRT} hemizygous assay to study DNA double-stranded break repair when assayed at 32oC or 38oC.

      (Wei and Rong, 2007)

      Mutants are sensitive to MMS.

      (Yamamoto et al., 2000)

      Homozygotes and hemizygotes do not show an increased frequency of spontaneous chromosome aberrations in neuroblast metaphases compared to wild-type larvae.

      (Gatti, 1979)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      mus101D2 is rescued by mus101+t9

      (Yamamoto et al., 2000)
      Not rescued by

      mus101D2 is not rescued by mus101tB10

      (Yamamoto et al., 2000)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Boyd.

      Comments
      Comments

      Complements: l(1)dd4xr16

      (Barbosa et al., 2000)

      Complements: mus106D1.

      (Laurencon, 2001.7.23)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      101D2
      (Gatti, 1979)
      D2
      (Johnson-Schlitz et al., 2007)
      mus101D2
      (Kondo and Perrimon, 2011, Wei and Rong, 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (8)