FB2024_03 , released June 25, 2024
Allele: Dmel\rasl1
Open Close
General Information
Symbol
Dmel\rasl1
Species
D. melanogaster
Name
FlyBase ID
FBal0014411
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Viable at 17oC and 22oC, but lethal at 29oC. Effective lethal phase at 29oC is about 12 hr after pupation. Temperature-sensitive period for lethality begins midway through the third larval instar and ends around pupation. At 22oC the eye color of males is obviously mutant, whereas homozygous females are virtually indistinguishable from wild type. At 17oC the eye color of males and females is wild-type. Quantity of pteridines in the eye, testes and Malpighian tubules are altered at 29oC. Temperature-sensitive period for pigment production in the Malpighian tubules occurs in the egg and first instar larva, and for the eyes and testes after pupation. For eyes the temperature sensitive period begins 52-56 hr after pupation. The effect in the eyes is autonomous. For testes the temperature sensitive period begins 56-60 hr after pupation.

temperature-sensitive lethal

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer

Grigliatti, 1970.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (2)