FB2024_03 , released June 25, 2024
Allele: Dmel\slp11
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General Information
Symbol
Dmel\slp11
Species
D. melanogaster
Name
FlyBase ID
FBal0015710
Feature type
allele
Associated gene
Dmel\slp1
Associated Insertion(s)
Carried in Construct
Also Known As
slpIIM105, slp1
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Grossniklaus et al., 1992)
Mutagen
ethyl methanesulfonate
(Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The labial lobe is absent in mutant embryos.

      (Rusch and Kaufman, 2000)

      Homozygotes display a weak cuticle phenotype affecting the odd numbered segments.

      (Grossniklaus et al., 1992)

      Even numbered denticle bands missing.

      (Jack et al., 1988)

      Partial deletion of odd naked cuticle.

      (Carroll and Scott, 1986)

      weak embryonic lethal. Embryos lack parts of naked cuticle of T2, A1, A3, A5 and A7 in an irregular fashion. No effect on ftz expression (Carroll and Scott, 1986).

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      slp1A10

      (de Belle et al., 1993)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (3)
      Notes on Origin
      Discoverer
      Comments
      Comments

      prd RNA expression has been studied in slp11 embryos.

      (Baumgartner and Noll, 1990)

      Phenotypic analysis of different slp1 and slp2 alleles establishes an allelic series: slp11 < slp1Δ41E < slp1A509 < slp13 < slp1Δ46G < slp2Δ66C < slp1Δ34B = slp2Δ34B.

      (Grossniklaus et al., 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      References (13)