FB2024_03 , released June 25, 2024
Allele: Dmel\tll2
Open Close
General Information
Symbol
Dmel\tll2
Species
D. melanogaster
Name
FlyBase ID
FBal0016890
Feature type
allele
Associated gene
Dmel\tll
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Casanova, 1990, Strecker et al., 1988, Strecker et al., 1986)
Mutagen
spontaneous
(Strecker et al., 1986)
X ray
(Diaz et al., 1996)
Progenitor genotype
Caused by aberration
In(3R)tll
Cytology
Description

Inversion breakpoint disrupts the proximal promoter region.

(Diaz et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos always have abdominal segment 8. Hindgut is of intermediate size.

      (Diaz et al., 1996)

      Anteriorly the cephalopharyngeal skeleton is normal, posteriorly the eighth abdominal denticle belt is reduced. Small increase in segment length.

      (Strecker et al., 1988)

      The telson is missing in homozygous tll2 or tll2/tll1 embryos.

      (Strecker et al., 1986)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Severity of the embryonic phenotype (deletion of either external structures, A8 or anal pads, or internal structures, hindgut) places tll alleles in the order: Df(3R)tll-pgx > tlll49 > tll1 > tlll29 > tll2 > tllle3.

      (Diaz et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      tll2
      Name Synonyms
      Secondary FlyBase IDs
        References (5)