abnormal locomotor behavior | adult stage (with ptchdl)
lethal | recessive
lethal - all die during embryonic stage
some die during embryonic stage
viable (with ptchdl)
adult external head (with ptchdl)
adult head capsule (with ptchdl)
ptchdl animals transheterozygous for ptc12 are viable with lowly penetrant headcase defects and show lowly penetrant locomotor defects in adulthood.
75% of ptchdl/ptc12 transheterozygotes show head capsule defects.