FlyBase Allele Report: Dmel\Abd-B[iab7-R73]

General Information

Symbol

Dmel\Abd-B^iab7-R73

Species

D. melanogaster

Name

FlyBase ID

FBal0028679

Feature type

allele

Associated gene

Dmel\Abd-B

Associated Insertion(s)

Carried in Construct

Also Known As

iab7^R73

Key Links

Allele class

loss of function allele

Mutagen

X ray

Nature of the Allele

Allele class

loss of function allele

(Galloni et al., 1993)

Mutagen

X ray

(Gyurkovics et al., 1990)

Progenitor genotype

Abd-B^Fab7-1

(Gyurkovics et al., 1990)

Cytology

Description

Contains the same deletion as the Abd-B^Fab7-1 progenitor in addition to the ~800bp deletion.

(Mihaly et al., 2006)

806bp deletion that removes the entire Abd-B-PTS (Abd-B promoter targeting sequence).

(Zhou and Levine, 1999)

270 bp deletion.

(Galloni et al., 1993)

Deletion of 1kb at position +143 to +144.

(Gyurkovics et al., 1990)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | homeotic

(Hendrickson and Sakonju, 1995)

visible | homeotic (with Df(3R)Abd-B^S10)

(Zhou and Levine, 1999)

Phenotype Manifest In

abdominal segment 6

(Gyurkovics et al., 1990)

abdominal segment 7

(Gyurkovics et al., 1990)

abdominal tergite 5 (with Df(3R)Abd-B^S10)

(Zhou and Levine, 1999)

abdominal tergite 6 (with Df(3R)Abd-B^S10)

(Zhou and Levine, 1999)

abdominal tergite 7 (with Df(3R)Abd-B^S10)

(Zhou and Levine, 1999)

adult abdominal segment 6

(Hendrickson and Sakonju, 1995)

adult abdominal segment 7

(Hendrickson and Sakonju, 1995)

Detailed Description

Statement

Reference

Heterozygous adult males have a normal abdominal pigmentation pattern. Abd-B^iab7-R73/Df(3R)Abd-B^S10 males show abdominal transformations; the A7 tergite is fully developed in these animals, and both A6 and A7 show pigmentation defects that resemble intermediates of the A4 and A5 patterns. The A5 tergite shows the A4 pigmentation pattern, as indicated by a complete loss of pigment in the anterior half of the dorsal cuticle.

(Zhou and Levine, 1999)

Segments A6 and A7 show a more posterior identity when heterozygous with Abd-B^- than when hemizygous.

(Hendrickson and Sakonju, 1995)

A6 and A7 are transformed to A5.

(Gyurkovics et al., 1990)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Phenotype may be due to a defect in some aspects of the maintenance function, rather than the lack of a specific enhancer.

(Galloni et al., 1993)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Abd-B^iab7-R73

Fab-7R73

(Hendrickson and Sakonju, 1995)

R73

(Barges et al., 2000)

iab-7^R73

(Zhou and Levine, 1999)

iab7^R73

(Galloni et al., 1993, Gyurkovics et al., 1990)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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