FlyBase Allele Report: Dmel\H[99]

General Information

Symbol

Dmel\H⁹⁹

Species

D. melanogaster

Name

FlyBase ID

FBal0029823

Feature type

allele

Associated gene

Dmel\H

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - genetic evidence

Mutagen

X ray

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Nagel et al., 2000)

Mutagen

X ray

(Maier et al., 1992)

Progenitor genotype

Cytology

Polytene chromosomes normal.

(Maier et al., 1992)

Description

1.5kb deletion towards the 3' end of the gene which may affect the 3' portion of the H protein.

(Maier et al., 1992)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Maier et al., 1992)

visible (with H^P8)

(Nagel et al., 2000)

visible | dominant

(Maier et al., 1992)

Phenotype Manifest In

tormogen cell | ectopic (with H^P8)

(Nagel et al., 2000)

trichogen cell (with H^P8)

(Nagel et al., 2000)

Detailed Description

Statement

Reference

In H⁹⁹/H^P8 flies causes transformations of external cells to double sockets.

(Nagel et al., 2000)

Strong phenotype.

(Maier et al., 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

H⁹⁹/H^P8 has trichogen cell phenotype, suppressible by Scer\GAL4^sca-537.4/numb^UAS.cWa

(Nagel et al., 2000)

H⁹⁹/H^P8 has tormogen cell | ectopic phenotype, suppressible by Scer\GAL4^sca-537.4/numb^UAS.cWa

(Nagel et al., 2000)

H⁹⁹ has phenotype, suppressible by sno^71e3

(Coyle-Thompson and Banerjee, 1993)

Suppressor of

Statement

Reference

H⁹⁹ is a suppressor of phenotype of sno^71e3

(Coyle-Thompson and Banerjee, 1993)

Additional Comments

Genetic Interactions

Statement

Reference

the addition of numb^Scer\UAS.cWa driven by Scer\GAL4^sca-537.4 to H⁹⁹/H^P8 flies rescues the double socket phenotype seen in the external sensory organs in these flies.

(Nagel et al., 2000)

H⁹⁹ and sno^71e3 show a mutually suppressive interaction.

(Coyle-Thompson and Banerjee, 1993)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

H⁹⁹ is rescued by H^HBS

(Maier et al., 1992)

Comments

H^HBS recombined onto the H⁹⁹ chromosome rescues the bristle phenotype completely.

(Maier et al., 1992)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Phenotypic series of H alleles, progressing from strongest (amorphic) to weakest mutant phenotype: H^B79 = H⁸¹ >> H¹ = H⁹⁹ > H^bob > H^94a > H^88d > H^B8 > H² >= H³ > H^A120.

(Maier et al., 1992)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

H⁹⁹

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

Open Close