FB2024_03 , released June 25, 2024
Allele: Dmel\wg17en40cP1
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General Information
Symbol
Dmel\wg17en40cP1
Species
D. melanogaster
Name
FlyBase ID
FBal0033174
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
wg17en40, wglacZ, wg-lacZ
Key Links
Nature of the Allele
Progenitor genotype
Associated Insertion(s)
Cytology
Description

Insertion of Ecol\lacZ enhancer trap element into wg.

Allele components
Component
Use(s)
Inserted element
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

wg17en40cP1/wgl-16 flies show the loss of nearly all pseudotracheae, which are structurally characteristic of the distiproboscis. These flies show no significant loss of taste bristles nor any significant change in mediproboscis morphology.

wg1/wg17en40cP1 wing discs show replacement of wing by a duplication of notum structures, which is also seen in the adult flies.

Proctodeal invagination is almost normal until stages 9-10, but much of the proctodeum (except the anterior-most region including the small intestine) begins to degenerate after the onset of germband shortening, resulting in a very tiny epithelial sac. The anal pads also degenerate.

30% of wgP/wg17en40cP1 flies show development of wing-like structures on the prothoracic segment, ranging from rudimentary to well formed.

A maximum of 5 of the 11 notal bristles (the posterior postalar, and the anterior and posterior dorsocentral and scutellar bristles) is sensitive to non-permissive conditions in wgl-12/wg17en40cP1. Dorsocentral, scutellar and posterior postalar bristles are not rescued by down shift after the late third instar. The sensory bristles of the wing are also temperature sensitive during the late third instar and early prepupal stages: the wing blade is of a normal size but is devoid of marginal structures. In wild type discs, but not in wgl-12/wg17en40cP1 discs, cells near the presumptive wing margin stop DNA replication shortly before pupariation.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments

Allele generated in the lab of N. Perrimon.

Used in mosaic analysis in the wing to examine expression of wg in cells outside the normal domain of wg expression.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (15)