FB2024_03 , released June 25, 2024
Allele: Dmel\lphA1
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General Information
Symbol
Dmel\lphA1
Species
D. melanogaster
Name
FlyBase ID
FBal0035193
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Associated Insertion(s)
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous larvae are negatively photokinetic with a stimulus indice significantly higher than wild type control. Heterozygotes have an indice similar to wild type, transheterozygotes with lphA2 have a higher indice. Homozygotes respond normally to light in a phototaxis assay, ERG is normal, males perform vigorous courtship in response to wild type females and perform the behaviour 'orientation', rarely performed by blind or visually impaired males. Hemizygotes are blind. Mutation does not affect larval responses to olfactory or taste stimuli.

Larvae are blind or show reduced response in a photokinesis assay. Adults have a wild type visual behaviour with respect to courtship, and normal ERGs.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

P-element can be excised by transposase.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
lphA1
Name Synonyms
Secondary FlyBase IDs
    References (2)