FB2024_03 , released June 25, 2024
Allele: Cbeta\DTA-E148S.Acp95EF
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General Information
Symbol
Cbeta\DTA-E148S.Acp95EF
Species
L. Corynephage beta
Name
FlyBase ID
FBal0040453
Feature type
allele
Associated gene
Cbeta\DT
Associated Insertion(s)
Carried in Construct
P{mc/DTA-S}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Kalb et al., 1993)
Progenitor genotype
Carried in construct
P{mc/DTA-S}
Cytology
Description

1.1kb Acp95EF upstream and transcribed sequences drive expression of DT-A(E148S).

(Kalb et al., 1993)
Allele components
Component
Use(s)
Regulatory region(s)
Acp95EF
Encoded product / tool
DT-A(E148S)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Males seminal fluid contains 'reduced' main-cell products. Female recipients of 'full' main-cell products (tud1) have significantly shorter lifespans than female recipients of 'reduced' (Cbβ\DT-AE148S.Acp95EF) or 'greatly reduced' main-cell products (Cbβ\DT-AE148D.Acp95EF), although they mated significantly less frequently.

      (Chapman et al., 1995)

      Females mated to Cbβ\DT-AE148S.Acp95EF males show defects in the stimulation of egg laying that normally occurs after mating, showing only short-term stimulation of the egg laying rate compared to females mated to control males.

      (Kalb et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Cbβ\DT-A has 300 fold lower activity level.

      (Chapman et al., 1995, Kalb et al., 1993)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Cbeta\DT-AE148S.Acp95EF
      Cbeta\DTA-E148S.Acp95EF
      Cbeta\DTE148S.Acp95EF
      Cbβ\DT-AE148S.Acp95EF
      Name Synonyms
      Secondary FlyBase IDs
        References (3)