FB2024_03 , released June 25, 2024
Allele: Mmus\PrkacaAct5C.PJ
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General Information
Symbol
Mmus\PrkacaAct5C.PJ
Species
M. musculus
Name
Actin 5C promoter construct of Jiang
FlyBase ID
FBal0042692
Feature type
allele
Associated gene
Mmus\Prkaca
Associated Insertion(s)
Carried in Construct
P{Act5C(-FRT)PKA.A902}
Transgenic product class
missense_variant
(Jiang and Struhl, 1995)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Jiang and Struhl, 1995)
Mutagen
FLPase
(Jiang and Struhl, 1995)
Progenitor genotype
Mmus\PrkacaFRT.Act5C
(Jiang and Struhl, 1995)
Carried in construct
P{Act5C(-FRT)PKA.A902}
Cytology
Description

FRT cassette has been excised, juxtaposing Act5C promoter with mutated Mmus\Prkaca coding sequences.

(Jiang and Struhl, 1995)
Allele components
Component
Use(s)
Regulatory region(s)
Act5C
Encoded product / tool
Mmus\Prkaca
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Zygotes carrying P{Act5C(-FRT)PKA.A902} do not survive to adulthood.

      (Jiang and Struhl, 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Clones of Pka-C1E95 that carry a single copy of Mmus\PkacaAct5C.PJ are generated in the wing disc, dpp is not ectopically expressed. Sibling clones in the adult mesoderm demonstrate rescue of the Pka-C1E95 mutant phenotype, normal notum patterns.

      (Jiang and Struhl, 1995)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Exists in clones, not reported as being germ-line transmitted.

      (Jiang and Struhl, 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Mmus\PkacaAct5C.PJ
      Mmus\PrkacaAct5C.PJ
      PKAAct5C.PJ
      Name Synonyms
      Actin 5C promoter construct of Jiang
      Secondary FlyBase IDs
        References (1)