FB2024_03 , released June 25, 2024
Allele: Dmel\mbcS4
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General Information
Symbol
Dmel\mbcS4
Species
D. melanogaster
Name
FlyBase ID
FBal0044177
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Embryos lie motionless in the vitelline membrane and fail to hatch. Examination with polarised light reveals a lack of differentiated muscle. Myoblasts fail to fuse. At 13 to 14 hours of development the myoblasts lie in a segmental array. At 16 to 17 hours of development the myoblasts fall into two populations, stretched and rounded. Stretched myoblasts first appear at around 11 hours after egg laying, and eventually can span distances two or three times the length of normal muscles. They often occur at positions and in orientations reminiscent of wild type muscle precursors. Only very few fusions occur. Segregation and movement of slou-expressing founder cells and vg-expressing cells is normal.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Epidermal development and differentiation are normal.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
mbcS4
Name Synonyms
Secondary FlyBase IDs
    References (1)