decreased fecundity | female (with mxcG46)
decreased fecundity | female (with mxcM1)
mxcSO/mxc22a-6 females die as pharate adults with extremely reduced eyes and head structures. Antennal segments 1 and 2 appear normal, whereas antennal segment 3, the arista and maxillary palps are reduced. Head structures derived from the labial and clypeo-labial discs, such as the proboscis, labrum and clypeus appear normal. These flies have melanotic spots.
mxcG9/mxcSO females have fewer egg chambers than wild-type flies, but are fully fertile and fecund. mxcM1/mxcSO and mxcG46/mxcSO females do not lay eggs. Some egg chambers contain the normal number of nurse cells, but oogenesis appears arrested before stage 7-8. Egg chambers degenerate in older flies. Lethal in combination with mxcG43.
Larvae show invasive blood cell tumors. Rare adult escapers show variably penetrant homeotic transformations. The eye transformation resembles that of Dfd1. Female heterozygotes with mxcG46 or mxcG43 are devoid of germ line. Most mxcG48 heterozygotes with mxc1 or mxcSO die in the third instar with blood cell tumors.
The alleles of mxc form a series. From weakest phenotype to strongest phenotype: mxcG9 < mxcM1 < mxcG46 < mxcG43 < mxcSO < mxc1 < mxcG48.