FB2024_03 , released June 25, 2024
Allele: Dmel\scsfl.cKa
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General Information
Symbol
Dmel\scsfl.cKa
Species
D. melanogaster
Name
full length construct a of Kellum
FlyBase ID
FBal0046421
Feature type
allele
Associated gene
scs
Associated Insertion(s)
Carried in Construct
P{Mcp-w#15}
P{wRW.SCSa}
P{wRW.ΔPst.SCS}
Also Known As
CRE-luc, UAS-rtTA, CRE-luciferase
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Sigrist and Pirrotta, 1997, Cai and Levine, 1995, Vazquez and Schedl, 1994, Kellum and Schedl, 1992)
Progenitor genotype
Carried in construct
P{3xCRE-LUC.B}
P{3xmCRE-LUC.B}
P{Act5C-rtTA-M2-alt}
P{btd.FRT.RV-2ndB}
P{btd.FRT.W1}
P{FRT(EnScsOff)}
P{FRT(ScsEnGypOff)}
P{FRT(ScsEnOff)}
P{FRT(ScsEnScsOff)}
P{FRT(Scs-mini-Off)}
P{FRT(whs)Scs-In}
P{Mcp-w#15}
P{PSM}
P{rtTA-alt}
P{scs<:hsp70:lacZ}
P{scs>:hsp70:lacZ}
P{scs>Yp1-lacZ}
P{scs-w.cKa}
P{scs-w.cKb}
P{scs-w-scs'.cKa}
P{scs-w-scs'.cKb}
P{SmwS'}
P{St.3-scs1.8-St.2}
P{Sxl-Pe:bcd}
P{Sxl-Pe:hb}
P{UAS-rtTA-M2-alt}
P{w+RK3}
P{wmut1RK3}
P{wRW.SCSa}
P{wRW.ΔPst.SCS}
P{Yp1-scs<lacZ}
P{Yp1-scs>lacZ}
Cytology
Description

1.8kb BamHI-BglII fragment containing scs sequences.

(Sigrist and Pirrotta, 1997)

Full length 1.8kb scs insulator.

(Cai and Levine, 1995)

Construct: 1.8kb of scs sequences.

(Vazquez and Schedl, 1994)

Full length 1.8kb BamHI-BglII scs insulator.

(Kellum and Schedl, 1992)
Allele components
Component
Use(s)
Encoded product / tool
scs
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      IT system uses scs to prevent expression of the coding region of interest from the region specific enhancer.

      (Wimmer et al., 1997)

      scsfl.cKa can act as an insulator, blocking repression by a Ubx Polycomb response element (PRE) as in the wPSM allele.

      (Sigrist and Pirrotta, 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      scsfl.cKa
      Name Synonyms
      full length construct a of Kellum
      (Kellum and Schedl, 1992)
      Secondary FlyBase IDs
        References (17)