FlyBase Allele Report: Dmel\wg[spd-j2]

General Information

Symbol

Dmel\wg^spd-j2

Species

D. melanogaster

Name

FlyBase ID

FBal0050829

Feature type

allele

Associated gene

Dmel\wg

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Neumann and Cohen, 1996, Neumann and Cohen, 1996)

Progenitor genotype

wg^rO727

(Neumann and Cohen, 1996, Neumann and Cohen, 1996)

Caused by aberration

Df(2L)spd^j2

Cytology

Description

Imprecise excision of the P{PZ} element of wg^rO727, deletion breakpoint is 100bp 5' of the wg transcription start site. wg transcript is untouched.

(Neumann and Cohen, 1996)

Imprecise excision of the P{PZ} element of wg^rO727, deletion breakpoint is 100bp 5' of the wg transcription start site.

(Neumann and Cohen, 1996)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | recessive

(Neumann and Cohen, 1996)

some die during embryonic stage | recessive

(Neumann and Cohen, 1996)

Phenotype Manifest In

Detailed Description

Statement

Reference

Heterozygotes with wg^l-17 are embryonic lethal. Heterozygotes with wg^spd-fg produce a hinge phenotype indistinguishable from wg^spd-fg homozygotes.

(Neumann and Cohen, 1996)

wg^l-17/wg^Sp-1 flies are viable and exhibit loss of anterior dorsocentrals, loss of microbristles located in the wg-expression domain of the notum and loss of distal antennal segments. Individuals in combination with wg^Sp-revP are pupal lethal, in combination with wg^l-17 are embryonic lethal and in combination with wg^P die before pupariation. Individuals are adult viable and exhibit the wing phenotype when in combination with wg¹. When in combination with wg^l-16 individuals are lethal, escapers lack antennae and the first pair of legs.