Reduces crossing over to a frequency similar to mei-2181, 3-7% of wild type. Reduction in crossing over is twofold less in the centromere proximal regions compared to the distal regions. High levels of nondisjunction on the X chromosome, lower levels on the 4th chromosome.
A small but significant proportion of eggs produced by mei-2181/mei-2188 ; yemα1/Df(3R)3450 females are able to develop into adults. These exceptional adults do not display paternal chromosome markers, suggesting that they have developed from diploid gametes that have undergone gynogenesis, a form of parthenogenesis that requires fertilisation.