FlyBase Allele Report: Dmel\Low[1]

General Information

Symbol

Dmel\Low¹

Species

D. melanogaster

Name

FlyBase ID

FBal0063133

Feature type

allele

Associated gene

Low

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

loss of function allele

Mutagen

gamma ray

Nature of the Allele

Allele class

loss of function allele

(Bhadra et al., 1997)

Mutagen

gamma ray

(Bhadra et al., 1997)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Pal Bhadra et al., 1998, Bhadra et al., 1997)

suppressor of variegation, with In(1)w^m4h

(Bhadra et al., 1998)

suppressor of variegation | dominant, with In(1)w^m4h

(Bhadra et al., 1997)

suppressor of variegation | dominant, with In(1)y^3P

(Bhadra et al., 1997)

Phenotype Manifest In

pigment cell

(Pal Bhadra et al., 1998)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Low¹ is an enhancer of abnormal eye color phenotype of w^DZL

(Bhadra et al., 1997)

Low¹ is an enhancer of abnormal eye color | recessive phenotype of w^bf2

(Bhadra et al., 1997)

Low¹ is an enhancer of abnormal eye color | recessive phenotype of w^bf

(Bhadra et al., 1997)

Low¹ is an enhancer of abnormal eye color | recessive phenotype of w^bl

(Bhadra et al., 1997)

Suppressor of

Statement

Reference

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^IR4

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^IR3

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^IR2

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^IR5

(Bhadra et al., 1997)

Low[+]/Low¹ is a suppressor of visible phenotype of Bar^unspecified

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^col

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^IR1

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^IR6

(Bhadra et al., 1997)

Low¹ is a suppressor of visible | dominant phenotype of L^unspecified

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^a2

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^Adh.PB

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^Bwx

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^a

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^a3

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^cf

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^co

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^h

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^sat

(Bhadra et al., 1997)

Low¹ is a suppressor of abnormal eye color | recessive phenotype of w^sp55

(Bhadra et al., 1997)

NOT Suppressor of

Statement

Reference

Low¹ is a non-suppressor of lethal | recessive | male phenotype of msl-3^unspecified

(Bhadra et al., 1997)

Low¹ is a non-suppressor of lethal | female phenotype of Sxl^fhv1/Sxl^f1

(Bhadra et al., 1997)

Other

Statement

Reference

Low¹, w^a, z¹ has abnormal eye color phenotype

(Bhadra et al., 1997)

Phenotype Manifest In

Suppressed by

Statement

Reference

Low¹ has phenotype, suppressible by Wow^γb

(Pal Bhadra et al., 1998)

Enhancer of

Statement

Reference

Wow^unspecified/Low¹ is an enhancer of phenotype of w^sp1

(Bhadra et al., 1998)

Mow^EMS/Low¹ is an enhancer of phenotype of w^crr

(Bhadra et al., 1998)

Low¹/Pcf11^EMS2 is an enhancer of phenotype of w^sp1

(Bhadra et al., 1998)

Wow^unspecified, Mow^EMS, Low¹, Pcf11^EMS2 is an enhancer of phenotype of w^sp1

(Bhadra et al., 1998)

Low¹ is an enhancer of pigment cell phenotype of w^DZL

(Bhadra et al., 1997)

Low¹ is an enhancer of pigment cell phenotype of w^bf2

(Bhadra et al., 1997)

Low¹ is an enhancer of pigment cell phenotype of w^bf

(Bhadra et al., 1997)

Low¹ is an enhancer of pigment cell phenotype of w^bl

(Bhadra et al., 1997)

NOT Enhancer of

Statement

Reference

Low¹ is a non-enhancer of phenotype of w^sp1

(Bhadra et al., 1998, Bhadra et al., 1997)

Mow^EMS/Low¹ is a non-enhancer of phenotype of w^sp1

(Bhadra et al., 1998)

Low¹ is a non-enhancer of phenotype of z¹

(Bhadra et al., 1998)

Wow^unspecified, Low¹, Pcf11^EMS2 is a non-enhancer of phenotype of w^sp1

(Bhadra et al., 1998)

Mow^EMS, Low¹, Pcf11^EMS2 is a non-enhancer of phenotype of w^sp1

(Bhadra et al., 1998)

Low¹ is a non-enhancer of phenotype of w^sp81d

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^zm

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^+mF

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^a59k1

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^ric

(Bhadra et al., 1997)

Low[+]/Low¹ is a non-enhancer of phenotype of r^sP1

(Bhadra et al., 1997)

Low¹ is a non-enhancer of eye phenotype of Kr^If-1

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^BgB+173

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^a4

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^-113

(Bhadra et al., 1997)

Low¹ is a non-enhancer of eye phenotype of Dr^unspecified

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^sp3

(Bhadra et al., 1997)

Low[+]/Low¹ is a non-enhancer of phenotype of Polr2A⁹⁶

(Bhadra et al., 1997)

z¹/Low¹ is a non-enhancer of phenotype of w^is

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of wⁱ

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^aR84h

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^e

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^sp2

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^apl

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^aM

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^sp4

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^Z4-17

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^+mSC

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^+mC

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^E

(Bhadra et al., 1997)

Low¹ is a non-enhancer of phenotype of w^c

(Bhadra et al., 1997)

Suppressor of

Statement

Reference

Low¹ is a suppressor of phenotype of w^crr

(Bhadra et al., 1998)

Wow^unspecified/Low¹ is a suppressor of phenotype of w^crr

(Bhadra et al., 1998)

Low¹/Pcf11^EMS2 is a suppressor of phenotype of w^crr

(Bhadra et al., 1998)

Wow^unspecified, Low¹, Pcf11^EMS2 is a suppressor of phenotype of w^crr

(Bhadra et al., 1998)

Mow^EMS, Low¹, Pcf11^EMS2 is a suppressor of phenotype of w^crr

(Bhadra et al., 1998)

Wow^unspecified, Mow^EMS, Low¹ is a suppressor of phenotype of w^crr

(Bhadra et al., 1998)

Wow^unspecified, Mow^EMS, Low¹, Pcf11^EMS2 is a suppressor of phenotype of w^crr

(Bhadra et al., 1998)

Wow^unspecified, Mow^EMS, Low¹ is a suppressor of phenotype of w^sp1

(Bhadra et al., 1998)

Low¹ is a suppressor of phenotype of Wow^γb

(Pal Bhadra et al., 1998)

Low¹ is a suppressor of phenotype of w^a

(Pal Bhadra et al., 1998)

Low¹ is a suppressor of pigment cell phenotype of w^IR4

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^IR3

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^IR2

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^IR5

(Bhadra et al., 1997)

Low[+]/Low¹ is a suppressor of eye phenotype of Bar^unspecified

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^col

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^IR1

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^IR6

(Bhadra et al., 1997)

Low¹ is a suppressor of eye phenotype of L^unspecified

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^a2

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^Adh.PB

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^Bwx

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^a

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^a3

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^cf

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^co

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^h

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^sat

(Bhadra et al., 1997)

Low¹ is a suppressor of pigment cell phenotype of w^sp55

(Bhadra et al., 1997)

w^a/Low¹ is a suppressor of phenotype of z¹

(Bhadra et al., 1997)

NOT Suppressor of

Statement

Reference

Low¹ is a non-suppressor of phenotype of z¹

(Bhadra et al., 1998, Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^sp1

(Bhadra et al., 1998, Bhadra et al., 1997)

Mow^EMS/Low¹ is a non-suppressor of phenotype of w^sp1

(Bhadra et al., 1998)

Wow^unspecified, Low¹, Pcf11^EMS2 is a non-suppressor of phenotype of w^sp1

(Bhadra et al., 1998)

Mow^EMS, Low¹, Pcf11^EMS2 is a non-suppressor of phenotype of w^sp1

(Bhadra et al., 1998)

Low¹ is a non-suppressor of phenotype of w^aR84h

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^E

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^Z4-17

(Bhadra et al., 1997)

Low¹ is a non-suppressor of eye phenotype of Dr^unspecified

(Bhadra et al., 1997)

Low¹ is a non-suppressor of eye phenotype of Kr^If-1

(Bhadra et al., 1997)

Low[+]/Low¹ is a non-suppressor of phenotype of Polr2A⁹⁶

(Bhadra et al., 1997)

Low[+]/Low¹ is a non-suppressor of phenotype of r^sP1

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^+mC

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^+mF

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^+mSC

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^-113

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^c

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^BgB+173

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^a4

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^apl

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^e

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of wⁱ

(Bhadra et al., 1997)

z¹/Low¹ is a non-suppressor of phenotype of w^is

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^ric

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^zm

(Bhadra et al., 1997)

w^is/Low¹ is a non-suppressor of phenotype of z¹

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^a59k1

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^sp3

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^sp2

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^sp81d

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^aM

(Bhadra et al., 1997)

Low¹ is a non-suppressor of phenotype of w^sp4

(Bhadra et al., 1997)

Other

Statement

Reference

Low¹, w^a, z¹ has pigment cell phenotype

(Bhadra et al., 1997)

Low¹, w^a, z¹ has eye phenotype

(Bhadra et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

Low¹ mutants suppress mutant eye colour phenotype in w^crr mutants and has no effect on mutant eye colour phenotype in w^sp1 mutants. Low¹, Wow^unspecified mutants suppress mutant eye colour phenotype in w^crr mutants and enhance mutant eye colour phenotype in w^sp1 mutants. Low¹, Mow^EMS mutants enhance mutant eye colour phenotype in w^crr mutants and have no effect on mutant eye colour phenotype in w^sp1 mutants. Low¹, Inr-a^EMS2 mutants suppress mutant eye colour phenotype in w^crr mutants and enhance mutant eye colour phenotype in w^sp1 mutants. Low¹, Inr-a^EMS2, Wow^unspecified mutants suppress mutant eye colour phenotype in w^crr mutants and have no effect on mutant eye colour phenotype in w^sp1 mutants. Low¹, Inr-a^EMS2, Mow^EMS mutants suppress mutant eye colour phenotype in w^crr mutants and have no effect on mutant eye colour phenotype in w^sp1 mutants. Low¹, Wow^unspecified, Mow^EMS mutants suppress mutant eye colour phenotype in w^crr and w^sp1 mutants. Low¹, Inr-a^EMS2, Wow^unspecified, Mow^EMS mutants suppress mutant eye colour phenotype in w^crr mutants and enhance mutant eye colour phenotype in w^sp1 mutants.

(Bhadra et al., 1998)

Low¹ is epistatic to Mow^EMS. Low¹ and Wow^γb mutually suppress the effect of the other.

(Pal Bhadra et al., 1998)

The lethality of Sxl^f1/Sxl^fhv1 females or msl-3^unspecified/msl-3^unspecified males is not affected by Low¹. The eye colour phenotype of w^a4, w^ric, w^aM, w^aR84h, w^a59k1, wⁱ, w^c, w^sp1, w^sp3, w^sp4, w^sp2, w^sp81d, w^e, w^ap-1, z¹ w^is, z¹ w^zm, z¹ Dp(1;1)w⁺61e19, w^E, w^+mF, w^+mSC, w^-113, w^Z4-17, w^+mC and w^BgB+173 flies is unaffected by a single copy of Low¹.

(Bhadra et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Low¹

Name Synonyms

Secondary FlyBase IDs

References (3)

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