FB2024_03 , released June 25, 2024
Allele: Dmel\inscΔ13
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General Information
Symbol
Dmel\inscΔ13
Species
D. melanogaster
Name
FlyBase ID
FBal0065829
Feature type
allele
Associated gene
Dmel\insc
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Hassan et al., 1998)
Progenitor genotype
inscP8
(Knirr et al., 1997)
insck07505
(Hassan et al., 1998)
Cytology
Description

Deletion removes 1kb exactly downstream from the site of the former insertion including part of the insc promoter, the first exon, the first exon/intron boundary and some intron sequences.

(Knirr et al., 1997)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:20,835,052..20,836,051 [-]
Comment:

Deletion removes 1kb exactly downstream from the site of the P{hsneo}inscP8 insertion.

(Knirr et al., 1997)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous embryos exhibit the insc muscle phenotype, for example lack of the lateral muscle. Muscle loss is due to defects in early somatic differentiation. Embryos also exhibit partial absence of parts of the chordotonal organs. Severe abnormalities are observed in a subset of pericardial cells.

      (Knirr et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Induced with: sktlΔ13.

      (Hassan et al., 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      inscΔ13
      Name Synonyms
      Secondary FlyBase IDs
        References (4)