FB2024_03 , released June 25, 2024
Allele: Dmel\HC21
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General Information
Symbol
Dmel\HC21
Species
D. melanogaster
Name
FlyBase ID
FBal0083440
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Heterozygotes exhibit shortening of wing vein L5.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

HC21 is a suppressor of visible phenotype of N55e11

HC21 is a suppressor of visible phenotype of Su(H)16

Other
Statement
Reference
Phenotype Manifest In
Enhancer of
Statement
Reference

HC21 is an enhancer of wing vein L4 phenotype of Egfrt1

Suppressor of
Statement
Reference

HC21 is a suppressor of wing phenotype of N55e11

HC21 is a suppressor of wing phenotype of Su(H)16

Other
Statement
Reference

Egfrt1, HC21 has adult thorax & microchaeta phenotype

HC21, groC105 has adult head & microchaeta phenotype

Egfrt1, HC21 has adult head & macrochaeta phenotype

Egfrt1, HC21 has adult thorax & macrochaeta phenotype

Egfrt1, HC21 has adult head & microchaeta phenotype

Additional Comments
Genetic Interactions
Statement
Reference

Mutation enhances the Egfr mutant wing phenotype, the interaction is not specific to Egfrt1. Egfrt1/Egfrt1; HC21/H+ flies exhibit reduced numbers of macrochaetae, most noticeably on the head.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
E(Egfr)C21
HC21
Name Synonyms
Secondary FlyBase IDs
    References (1)