FlyBase Allele Report: Dmel\Dref[UAS.cSa]

(Yoshioka et al., 2012, Trong-Tue et al., 2010, Ida et al., 2009, Nakamura et al., 2008, Ida et al., 2007, Phuong Thao et al., 2006, Yoshida et al., 2004, Hirose et al., 2001)

eye, with Scer\GAL4^ptc-559.1

(Yoshida et al., 2001)

eye disc | larval stage, with Scer\GAL4^GMR.PS

(Hirose et al., 2001)

eye disc | third instar larval stage

(Kim et al., 2007)

eye disc posterior to the morphogenetic furrow | larval stage, with Scer\GAL4^GMR.PS

(Hirose et al., 2001)

melanotic mass, with Scer\GAL4^Cg.PA

(Yoshida et al., 2001)

melanotic mass, with Scer\GAL4^insc-Mz1407

(Yoshida et al., 2001)

mitochondrial membrane | third instar larval stage, with Scer\GAL4^GMR.PS

(Kim et al., 2007)

ommatidium, with Scer\GAL4¹⁸⁵⁴

(Yoshida et al., 2001)

ommatidium, with Scer\GAL4^Act88F.PD

(Yoshida et al., 2001)

ommatidium, with Scer\GAL4^GMR.PS

(Hirose et al., 2001, Ohno et al., 2000)

ommatidium, with Scer\GAL4^ptc-559.1

(Yoshida et al., 2001)

photoreceptor cell R1, with Scer\GAL4^GMR.PS

(Hirose et al., 2001)

photoreceptor cell R6, with Scer\GAL4^GMR.PS

(Hirose et al., 2001)

photoreceptor cell R7, with Scer\GAL4^GMR.PS

(Hirose et al., 2001)

photoreceptor neuron, with Scer\GAL4^GMR.PS

(Trong-Tue et al., 2010, Hirose et al., 2001)

pigment cell, with Scer\GAL4^GMR.PS

(Hirose et al., 2001)

scutellar bristle | ectopic, with Scer\GAL4^ptc-559.1

(Park et al., 2008)

wing, with Scer\GAL4^ap-md544

(Yoshida et al., 2001)

wing, with Scer\GAL4^ptc-559.1

(Park et al., 2008)

wing blade posterior compartment, with Scer\GAL4^en-e16E

(Yoshida et al., 2001)

wing disc | dorsal, with Scer\GAL4^ap-md544

(Yoshida et al., 2001)

wing disc posterior compartment, with Scer\GAL4^en-e16E

(Yoshida et al., 2001)

wing margin, with Scer\GAL4^Dll-md23

(Yoshida et al., 2001)

wing vein L5 | distal, with Scer\GAL4^en-e16E

(Yoshida et al., 2004)

Detailed Description

Statement

Reference

Expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^GMR.PS results in a rough eye phenotype.

(Yoshioka et al., 2012, Phuong Thao et al., 2006)

Over-expression of Dref^Scer\UAS.cSa using either Scer\GAL4^sca-109-68 or Scer\GAL4^ac.13 does not induce ectopic sensory organ precursors nor macrochaetes in the adult thorax, nor ectopic campaniform sensilla on the L3 wing vein.

Over-expression of Dref^Scer\UAS.cSa using Scer\GAL4^sca-109-68 does not change the nuclear or nucleolar size of the posterior scutellar shaft cells.

(Kawamori and Yamaguchi, 2011)

Overexpression of Dref^Scer\UAS.cSa in the developing eye (under the control of Scer\GAL4^GMR.PS) induces ectopic DNA synthesis and apoptosis and inhibits photoreceptor cell differentiation in eye imaginal discs, such that adult flies exhibit a mild rough eye phenotype.

(Trong-Tue et al., 2010)

Scer\GAL4^GMR.PS Dref^Scer\UAS.cSa flies have a severe rough eye phenotype.

(Ida et al., 2009)

Scer\GAL4^GMR.PS-mediated expression of Dref^Scer\UAS.cSa results in a severe rough eye phenotype, though viability and fertility are normal.

(Nakamura et al., 2008)

Flies expressing Dref^Scer\UAS.cSa under the control of Scer\GAL4^ptc-559.1 show ectopic macrochaetae in the scutellum and a notching wing phenotype and reduction in the distance between the L3 and L4 wing veins.

(Park et al., 2008)

Flies expressing Dref^Scer\UAS.cSa under the control of Scer\GAL4^GMR.PS have a severe rough eye phenotype.

(Ida et al., 2007)

Dref^Scer\UAS.cSa-overexpression under the control of Scer\GAL4^GMR.PS induces apoptosis in eye imaginal disc cells. Overexpression of Scer\GAL4^GMR.PS>Dref^Scer\UAS.cSa also results in the loss of membrane potential seen in wild-type mitochondria.

(Kim et al., 2007)

Expression of Dref^Scer\UAS.cSa in the developing eye under the control of Scer\GAL4^GMR.PS results in a severe rough eye phenotype.

(Park et al., 2004)

Expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^GMR.PS results in a rough eye phenotype.

Expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^en-e16E results in an increase in the width of the distal end of wing vein L5.

(Yoshida et al., 2004)

Expression of Dref^Scer\UAS.cSa in the eye under the control of Scer\GAL4^GMR.PF causes severe eye degeneration, with loss of pigmentation.

(Kazemi-Esfarjani and Benzer, 2002)

Expression of Dref^Scer\UAS.cSa in the developing eye under the control of Scer\GAL4^GMR.PS leads to an adult eye which is severely rough in appearance and with most bristles missing. The organised array of each ommatidium is destroyed and some ommatidia are fused to each other. The number and shape of the photoreceptor cells in each ommatidia is also abnormal. Pigment cells are found to be missing in all ommatidia, and some remaining tissues are vacuolated.

No significant difference is seen between control and Dref^Scer\UAS.cSa-expressing flies (under the control of Scer\GAL4^GMR.PS) in the region anterior to the morphogenetic furrow, where the GMR promoter is inactive. In control discs, a 30-min pulse of BrdU incorporation leads to labeling of cells in one or two columns posterior to the morphogenetic furrow, while imaginal discs of transgenic flies expressing Dref^Scer\UAS.cSa labels the equivalent of five columns. Therefore expression of Dref^Scer\UAS.cSa expands the S phase or induces an extra S phase. Most of the nuclei of cells with BrdU incorporated occupy a more apical position in the imaginal discs than do nuclei in the synchronous S-phase cells posterior to the morphogenic furrow and in uncommitted cells, suggesting that Dref^Scer\UAS.cSa expression causes ectopic S phase in some cells that are normally postmitotic.

Expression of Dref^Scer\UAS.cSa in the developing eye under the control of Scer\GAL4^GMR.PS inhibits the differentiation of R1, R6 and R7 photoreceptor cells.

Transgenic flies expressing Dref^Scer\UAS.cSa in the developing eye under the control of Scer\GAL4^GMR.PS exhibit an increase in apoptotic cells in the region posterior to the morphogenetic furrow. Apoptosis seems to begin in the imaginal disc cells in the region where commitment to R1/R6 cells takes place, suggesting that failure of differentiation in to R1/R6 may induce apoptosis.

(Hirose et al., 2001)

Expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^Act88F.PD or Scer\GAL4^ptc-559.1 results in a rough eye phenotype. Expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4¹⁸⁵⁴ results in a weak rough eye phenotype. Expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^en-e16E results in a notched wing in the posterior compartment. Expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^ap-md544 results in a crumpled wing. Expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^dpp.blk1 results in notching of the wing between veins L3 and L4. Expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^Dll-md23 results in notching of the peripheral wing margin. Severe wing notching is seen in about 5% of flies. Expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^twi.PG, Scer\GAL4^prd.RG1, Scer\GAL4⁴⁹³⁵, Scer\GAL4^55B, Scer\GAL4¹⁸⁸², Scer\GAL4^rho.PL, Scer\GAL4^wg.PM, Scer\GAL4^elav.PLu, Scer\GAL4²⁶⁸⁹, Scer\GAL4^nos.PG or Scer\GAL4^l(1)BP-1 has no effect on wing morphology. Expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^en-e16E results in an increase in apoptotic cells in the posterior compartment of the wing disc. Expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^ap-md544 results in an increase in apoptotic cells in the dorsal region of the wing disc.

(Yoshida et al., 2001)

Overexpression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^GMR.PS results in a rough eye phenotype.

(Ohno et al., 2000)

Expression of Dref^CR1.Scer\UAS under the control of Scer\GAL4^hs.PB using heat shock causes lethality throughout developmental stages. The lethality is suppressed by coexpression of Dref^Scer\UAS.cSa.

(Hirose et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(1)HF368

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(2L)pr1

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(2L)A246

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(2L)b83d29a

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(2L)H20

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(2L)TW50

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(2L)VA12

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(2L)pr-A16

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(2L)Sd77

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(2R)M41A4

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Dll⁹/Dll[+]

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(2R)CA53

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(2R)en-SFX31

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(2R)Pu-D17

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(3L)Ar14-8

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(3R)ry615

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(3R)e-D7

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Dll⁵/Dll[+]

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(1)C128

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, enhanceable by Df(1)l15

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^en-e16E has visible phenotype, enhanceable by Df(2R)Jp1/+

(Yoshida et al., 2001)

Suppressed by

Statement

Reference

Dref^UAS.cSa, Scer\GAL4^GMR.PS has visible phenotype, suppressible | partially by bsk¹/bsk[+]

(Yoshioka et al., 2012)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has visible phenotype, suppressible | partially by bsk²/bsk[+]

(Yoshioka et al., 2012)

Dref^UAS.cSa has increased cell death phenotype, suppressible by p53[+]/p53^-ns

(Trong-Tue et al., 2010)

Dref^UAS.cSa has increased cell death phenotype, suppressible by p53^-ns/p53^-ns

(Trong-Tue et al., 2010)

Dref^UAS.cSa, Scer\GAL4^ptc-559.1 has visible phenotype, suppressible | partially by bib^RNAi.UAS, Scer\GAL4^ptc-559.1

(Park et al., 2008)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has visible phenotype, suppressible | partially by eIF-4a[+]/eIF4A⁰²⁴³⁹

(Ida et al., 2007)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has visible phenotype, suppressible by skpA[+]/SkpA¹

(Phuong Thao et al., 2006)

Dref^UAS.cSa, Scer\GAL4^en-e16E has visible phenotype, suppressible by phl[+]/Raf^E1

(Yoshida et al., 2004)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Diap1^GMR.PH

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Diap2^GMR.PH

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by E2f[+]/E2f1⁹¹

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by E2f[+]/E2f1⁰⁷¹⁷²

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by E2f[+]/E2f1^rM729

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by brm[+]/brm²

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by osa²/osa[+]

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by mor[+]/mor¹

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible | partially by E(Pc)¹

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Df(1)sqh

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Df(1)2-19

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Df(2L)al

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Df(2L)S3

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Df(2L)sc19-8

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Df(2L)dp-h25

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Df(2L)dp-h24

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Df(2L)cl-h3

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Df(2L)el80f1

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Df(2L)TE35D-2

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Df(2L)TE35D-13

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Df(2R)PC4

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Df(3L)W10

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by Df(3R)M-Kx1

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has increased cell death phenotype, suppressible by BacA\p35^GMR.PH

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^en-e16E has visible phenotype, suppressible by BEAF-32^UAS.cYa, Scer\GAL4^en-e16E

(Yoshida et al., 2001)

Dref^UAS.cSa, Scer\GAL4^en-e16E has visible phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^en-e16E

(Yoshida et al., 2001)

Dref^UAS.cSa, Scer\GAL4^en-e16E has visible phenotype, suppressible by Df(3L)H99/+

(Yoshida et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has visible phenotype, suppressible | partially by Mlf^UAS.cOa, Scer\GAL4^GMR.PS

(Ohno et al., 2000)

NOT suppressed by

Statement

Reference

Dref^UAS.cSa, Scer\GAL4^en-e16E has visible phenotype, non-suppressible by E2f[+]/E2f1⁹¹

(Yoshida et al., 2001)

NOT Suppressor of

Statement

Reference

Dref^UAS.cSa, Scer\GAL4^GMR.PF is a non-suppressor of visible phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^GMR.PF

(Martin-Lanneree et al., 2006)

Phenotype Manifest In

Enhanced by

Statement

Reference

Dref^UAS.cSa has eye phenotype, enhanceable by Scer\GAL4^GMR.PS/HP6^UAS.cIa

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by Df(1)C128/+

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by Tom40^G0216/Tom40[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by Ykt6[+]/Ykt6^G0155

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by fs(1)h^G0093/fs(1)h[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by mys[+]/mys^KG02930

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by mys[+]/mys^G0281

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by l(1)G0219[+]/l(1)G0219^G0219

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by l(1)G0228^G0228/l(1)G0228[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by Trf2[+]/Trf2^G0295

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by l(1)G0332[+]/l(1)G0332^G0332

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by l(1)G0372[+]/l(1)G0372^G0372

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by Trf2[+]/Trf2^G0425

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by dome^G0199b/dome[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by Phf7^KG09994/Phf7[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by l(1)G0196[+]/l(1)G0196^G0196

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by l(2)01855[+]/ds⁰¹⁸⁵⁵

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by S^k09530/S[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by l(2)k06107[+]/l(2)k06107^k06107

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by Df(2L)Prl/+

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by Df(2L)b83d29a/+

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by Df(2L)H20/+

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by Df(2L)TW50/+

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by pigeon[+]/pigeon^P1

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by Df(2L)pr-A16/+

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, enhanceable by Df(2R)Pu-D17/+

(Ida et al., 2009)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(1)HF368

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(2L)pr1

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(2L)A246

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(2L)b83d29a

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(2L)H20

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Dll⁹/Dll[+]

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(2L)TW50

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(2L)VA12

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(2L)pr-A16

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(2L)Sd77

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(2R)M41A4

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(2R)CA53

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(2R)en-SFX31

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(2R)Pu-D17

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(3L)Ar14-8

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(3R)ry615

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Dll⁵/Dll[+]

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(3R)e-D7

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(1)C128

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, enhanceable by Df(1)l15

(Hirose et al., 2001)

Dref^UAS.cSa has wing blade posterior compartment phenotype, enhanceable by Scer\GAL4^en-e16E/Df(2R)Jp1/+

(Yoshida et al., 2001)

NOT Enhanced by

Statement

Reference

Dref^UAS.cSa has eye phenotype, non-enhanceable by dpy^OVLR/dp[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, non-enhanceable by dpy^D/dp[+]

(Ida et al., 2009)

Suppressed by

Statement

Reference

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible | partially by bsk¹/bsk[+]

(Yoshioka et al., 2012)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible | partially by bsk²/bsk[+]

(Yoshioka et al., 2012)

Dref^UAS.cSa has eye phenotype, suppressible by p53[+]/p53^-ns

(Trong-Tue et al., 2010)

Dref^UAS.cSa has eye phenotype, suppressible by p53^-ns/p53^-ns

(Trong-Tue et al., 2010)

Dref^UAS.cSa has eye phenotype, suppressible by +/Df(2L)TE35D-2

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by Cul3⁰⁶⁴³⁰/Cul-3[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by +/Df(2L)TE35D-13

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by lace[+]/lace^k05305

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by J29[+]/J29^J29

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by Cyt-c-d^bln1/Cyt-c-d[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by RpS26⁰⁴⁵⁵³/RpS26[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by l(2)k07219^k07219/l(2)k07219[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by Df(2R)PC4/+

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by stau[+]/stau^ry9

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by Hsf⁰³⁰⁹¹/Hsf[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by l(2)08717[+]/MFS14⁰⁸⁷¹⁷

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by Xbp1[+]/Xbp1^k13803

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by CG10496[+]/TAF1C-like^07128a

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by MESK2^k00119/MESK2[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by HP6[+]/HP6^BG01429

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by Df(1)sqh/+

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by schlank^G0365/schlank[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by l(1)G0287[+]/l(1)G0287^G0287

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by +/Df(1)16-2-19

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by sw[+]/sw^KG05547

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by l(1)G0004^G0004/l(1)G0004[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by Df(2L)al/+

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by l(2)k06506[+]/l(2)k06506^k06506

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by l(2)k07308^k07308/l(2)k07308[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by Df(2L)S3/+

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by l(2)10685^k05810/l(2)10685[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by Df(2L)cl-h3/+

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by Kdm5^k06801/lid[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by eIF-4a[+]/eIF4A^k01501

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by eIF-4a[+]/eIF4A⁰²⁴³⁹

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by crol[+]/crol^k05205

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by Rab6[+]/Rab6^k13606

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, suppressible by l(2)k05448^k05448/l(2)k05448[+]

(Ida et al., 2009)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible | partially by osa²/osa[+]

(Nakamura et al., 2008)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible | partially by osa⁰⁰⁰⁹⁰/osa[+]

(Nakamura et al., 2008)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible | partially by mor[+]/mor¹

(Nakamura et al., 2008)

Dref^UAS.cSa, Scer\GAL4^ptc-559.1 has wing phenotype, suppressible | partially by bib^RNAi.UAS, Scer\GAL4^ptc-559.1

(Park et al., 2008)

Dref^UAS.cSa, Scer\GAL4^ptc-559.1 has scutellar bristle | ectopic phenotype, suppressible | partially by bib^RNAi.UAS, Scer\GAL4^ptc-559.1

(Park et al., 2008)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible | partially by eIF-4a[+]/eIF4A⁰²⁴³⁹

(Ida et al., 2007)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by skpA[+]/SkpA¹

(Phuong Thao et al., 2006)

Dref^UAS.cSa has eye phenotype, suppressible by Scer\GAL4^GMR.PS

(Park et al., 2004)

Dref^UAS.cSa, Scer\GAL4^en-e16E has wing vein L5 | distal phenotype, suppressible by phl[+]/Raf^E1

(Yoshida et al., 2004)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Diap1^GMR.PH

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Diap2^GMR.PH

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by E2f[+]/E2f1⁹¹

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by E2f[+]/E2f1⁰⁷¹⁷²

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by E2f[+]/E2f1^rM729

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by brm[+]/brm²

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by osa²/osa[+]

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by mor[+]/mor¹

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible | partially by E(Pc)¹

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Df(1)sqh

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Df(1)2-19

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Df(2L)al

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Df(2L)S3

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Df(2L)sc19-8

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Df(2L)dp-h25

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Df(2L)dp-h24

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Df(2L)cl-h3

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Df(2L)el80f1

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Df(2L)TE35D-2

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Df(2L)TE35D-13

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Df(2R)PC4

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Df(3L)W10

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by Df(3R)M-Kx1

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has eye phenotype, suppressible by BacA\p35^GMR.PH

(Hirose et al., 2001)

Dref^UAS.cSa, Scer\GAL4^en-e16E has wing blade posterior compartment phenotype, suppressible by BEAF-32^UAS.cYa, Scer\GAL4^en-e16E

(Yoshida et al., 2001)

Dref^UAS.cSa, Scer\GAL4^en-e16E has wing blade posterior compartment phenotype, suppressible by Df(3L)H99/+

(Yoshida et al., 2001)

Dref^UAS.cSa, Scer\GAL4^en-e16E has wing blade posterior compartment phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^en-e16E

(Yoshida et al., 2001)

Dref^UAS.cSa, Scer\GAL4^GMR.PS has ommatidium phenotype, suppressible | partially by Mlf^UAS.cOa, Scer\GAL4^GMR.PS

(Ohno et al., 2000)

NOT suppressed by

Statement

Reference

Dref^UAS.cSa has eye phenotype, non-suppressible by HP6[+]/HP6^BG01429rev

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, non-suppressible by dpy^OVLR/dp[+]

(Ida et al., 2009)

Dref^UAS.cSa has eye phenotype, non-suppressible by dpy^D/dp[+]

(Ida et al., 2009)

Dref^UAS.cSa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Mlf^UAS.cKa, Scer\GAL4^GMR.PF

(Kazemi-Esfarjani and Benzer, 2002)

Dref^UAS.cSa, Scer\GAL4^en-e16E has wing blade posterior compartment phenotype, non-suppressible by E2f1[+]/E2f1⁹¹

(Yoshida et al., 2001)

NOT Suppressor of

Statement

Reference

Dref^UAS.cSa, Scer\GAL4^GMR.PF is a non-suppressor of eye phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^GMR.PF

(Martin-Lanneree et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

The rough eye phenotype caused by expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^GMR.PS is weakly but significantly suppressed by bsk¹/+ and by bsk²/+.

(Yoshioka et al., 2012)

The rough eye phenotype caused by expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^GMR.PS is suppressed by p53^-ns/+ and by p53^-ns/p53^-ns (with stronger suppression in the homozygous background).

(Trong-Tue et al., 2010)

Flies heterozygous for osa², osa⁰⁰⁰⁹⁰ or mor¹ show suppression of the Scer\GAL4^GMR.PS, Dref^Scer\UAS.cSa severe rough eye phenotype; eyes are modestly rough and fused ommatidia are not apparent.

(Nakamura et al., 2008)

Expression of bib^{dsRNA.Scer\UAS} partially suppresses the ectopic scutellar macrochaetae, wing notching and reduction in distance between the L3 and L4 veins seen when Dref^Scer\UAS.cSa is expressed under the control of Scer\GAL4^ptc-559.1.

(Park et al., 2008)

The rough eye phenotype caused by expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^GMR.PS is partially suppressed by eIF-4a⁰²⁴³⁹/+.

(Ida et al., 2007)

skpA¹/+ suppresses the rough eye phenotype caused by expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^GMR.PS.

(Phuong Thao et al., 2006)

A Catⁿ¹/+ background suppresses the rough eye phenotype observed when Dref^Scer\UAS.cSa is expressed in the developing eye under the control of Scer\GAL4^GMR.PS.

(Park et al., 2004)

phl^E1/+ significantly suppresses the extra vein formation seen in flies expressing Dref^Scer\UAS.cSa under the control of Scer\GAL4^en-e16E.

(Yoshida et al., 2004)

Co-expression of Mlf^Scer\UAS.cKa with Dref^Scer\UAS.cSa in the eye under the control of Scer\GAL4^GMR.PF does not suppress the eye degeneration observed upon expression of Dref^Scer\UAS.cSa alone.

(Kazemi-Esfarjani and Benzer, 2002)

The rough eye phenotype seen upon expression of Dref^Scer\UAS.cSa in the developing eye under the control of Scer\GAL4^GMR.PS is suppressed with co-expression of th^GMR.PH or Iap2^GMR.PH.

The rough eye phenotype seen upon expression of Dref^Scer\UAS.cSa in the developing eye under the control of Scer\GAL4^GMR.PS is suppressed in an E2f⁹¹, E2f⁰⁷¹⁷², or E2f^rM729 heterozygous background.

A brm²/+, osa²/+, or mor¹/+ background significantly suppresses the rough eye phenotype found in flies expressing Dref^Scer\UAS.cSa under the control of Scer\GAL4^GMR.PS.

An E(Pc)¹ background weakly suppresses the rough eye phenotype found in flies expressing Dref^Scer\UAS.cSa under the control of Scer\GAL4^GMR.PS.

Genetic crossing of the Dref^Scer\UAS.cSa expressing strain with Dll⁹ results in a weakly enhanced rough eye phenotype.

Genetic crossing of the Dref^Scer\UAS.cSa expressing strain with Dll⁵ results in a severe small eye phenotype.

(Hirose et al., 2001)

Co-expression of Mlf^Scer\UAS.cOa at least partially rescues the rough eye phenotype caused by expression of Dref^Scer\UAS.cSa under the control of Scer\GAL4^GMR.PS.

(Ohno et al., 2000)

Xenogenetic Interactions

Statement

Reference

Co-expression of Dref^Scer\UAS.cSa with Zzzz\CAG^{63Q.Scer\UAS.T:Ivir\HA1} in the eye under the control of Scer\GAL4^GMR.PF does not suppress the eye degeneration observed upon expression of Zzzz\CAG^{63Q.Scer\UAS.T:Ivir\HA1} alone.

(Kazemi-Esfarjani and Benzer, 2002)

The rough eye phenotype seen upon expression of Dref^Scer\UAS.cSa in the developing eye under the control of Scer\GAL4^GMR.PS is suppressed by co-expression of BacA\p35^GMR.PH. Horizontal sections of eyes of adult flies shows that Dref^Scer\UAS.cSa-induced eye degeneration is partially suppressed by BacA\p35^GMR.PH expression.

(Hirose et al., 2001)

Complementation and Rescue Data

Rescues

Dref^UAS.cSa/Scer\GAL4^sca-109-68 rescues Dref^RNAi.h-h.UAS

(Kawamori and Yamaguchi, 2011)

Dref^UAS.cSa/Scer\GAL4^hs.PB rescues Dref^CR1.UAS

(Hirose et al., 1999)

Comments

Co-expression of Dref^Scer\UAS.cSa effectively rescues the bristle phenotypes resulting from Scer\GAL4^sca-109-68-mediated expression of Dref^{dsRNA.h-h.Scer\UAS} (insertion P{UAS-Dref.IR.h-h}15).

(Kawamori and Yamaguchi, 2011)

The lethality induced by the expression of Dref^CR1.Scer\UAS under the control of Scer\GAL4^hs.PB (and heat-shock) is suppressed by coexpression of Dref^Scer\UAS.cSa.

(Hirose et al., 1999)

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Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Dref^Scer\UAS.cSa

Dref^UAS.cSa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Sawado

(Sawado et al., 1998)

Secondary FlyBase IDs

References (24)

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