FB2024_03 , released June 25, 2024
Allele: Dmel\Lim3lacZ
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General Information
Symbol
Dmel\Lim3lacZ
Species
D. melanogaster
Name
FlyBase ID
FBal0094674
Feature type
allele
Associated gene
Dmel\Lim3
Associated Insertion(s)
Carried in Construct
P{Lim3.lacZ.T}
Also Known As
Lim3A-lacZ
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Thor et al., 1999)
Progenitor genotype
Carried in construct
P{Lim3.lacZ.T}
Cytology
Description

lacZ is fused to the 5' regulatory region and first three exons of Lim3.

(Thor et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
Lim3_A
Encoded product / tool
Lim3
Tagged with
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 16
      larval RP5 motor neuron
      (Thor et al., 1999)
      larval VO1 motor neuron
      (Thor et al., 1999)
      motor neuron | subset
      (Thor et al., 1999)
      larval VO2 motor neuron
      (Thor et al., 1999)
      larval VL3/4 motor neuron
      (Thor et al., 1999)
      interneuron | subset
      (Thor et al., 1999)
      Additional Information
      Statement
      Reference

      Studies using reporter constructs indicate that Lim3 expressing cells include a subset of interneurons and motor neurons including the RP motor neurons and a lateral cluster of motor neurons including MN14/30 and MN28, which innervate muscles 14 plus 30, and 28, respectively.

      (Thor et al., 1999)
       
      Marker for
      Reflects expression of
      Lim3
      (Thor et al., 1999)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Lim3T:Ecol\lacZ
      Lim3T:lacZ
      Lim3lacZ
      Name Synonyms
      Secondary FlyBase IDs
        References (5)