FB2024_03 , released June 25, 2024
Allele: Dmel\geminink09107
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General Information
Symbol
Dmel\geminink09107
Species
D. melanogaster
Name
FlyBase ID
FBal0101119
Feature type
allele
Associated gene
Dmel\geminin
Associated Insertion(s)
P{lacW}geminink09107
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}geminink09107
Cytology
Description

P{lacW} insertion at -61bp relative to the transcription start site.

(Quinn et al., 2001)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      100% of stage 12 geminink14019/geminink09107 ovaries show strong BrdU labeling in 4 amplification foci in all follicle cells (wild-type ovaries at this stage mostly have only one focus of DNA amplification per cell). By stage 14, all follicle cells of wild-type ovaries have ceased DNA amplification, but many follicle cells from 50% of mutant ovaries still continue DNA amplification.

      (Quinn et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Separable from: l(2)k09107k09107. The lethality of the "l(2)k09107" chromosome (caused by l(2)k09107k09107) is separable from the P{lacW}geminink09107 insertion.

      (Spradling, 1999.12.9)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      geminink09107
      l(2)k09107
      (Quinn et al., 2001)
      v(2)k09107
      (Spradling et al., 1999)
      v(2)k09107k09107
      (Spradling, 1999.12.9)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)