FB2024_03 , released June 25, 2024
Allele: Dmel\ftz-f119
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General Information
Symbol
Dmel\ftz-f119
Species
D. melanogaster
Name
FlyBase ID
FBal0122982
Feature type
allele
Associated gene
Dmel\ftz-f1
Associated Insertion(s)
Carried in Construct
Also Known As
ftz-f1ex19
Key Links
Allele class

loss of function allele

Mutagen
    Nature of the Allele
    Allele class

    loss of function allele

    (Fortier et al., 2003)
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        In ftz-f117/ftz-f119 animals the shape and size of 0-h prepupal leg imaginal discs are normal. The imaginal discs in 6-h prepupae are also normal. Mutant leg discs also show the successful transformation of cells from anisometric to isometric in the basitarsal and tibial segments.

        (Fortier et al., 2003)

        In ftz-f117/ftz-f119 mutant pupae 24 after pupariation formation (APF), DNA degradation is blocked. The intact salivary glands possess large cytoplasmic vacuoles reminiscent of the cell morphology of wild-type 12 hour salivary glands. Adult head eversion occurs normally in these animals.

        (Lee et al., 2002)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (4)
        Reported As
        Symbol Synonym
        Ftz-F1ex19
        (Vanderzwan-Butler et al., 2007)
        ftz-f119
        (Field et al., 2016, Hou et al., 2009)
        ftz-f1ex19
        (Moris-Sanz et al., 2015, Gates et al., 2004)
        βFTZ-F119
        (Lee and Baehrecke, 2001)
        Name Synonyms
        Secondary FlyBase IDs
          References (9)