Amino acid replacement: P?S. A single point mutation leads to the amino acid change P to S at amino acid number 1395 by the numbering of isoform 1 (ISO1; 5.1Kb), or 1496 by the numbering of isoform 2 (ISO2; 5.4Kb).
C12009088T
C?T
P1395S | rols-PA; P1726S | rols-PB; P1496S | rols-PC; P1395S | rols-PD; P1496S | rols-PE; P1495S | rols-PF; P1625S | rols-PG; P1394S | rols-PH; P1624S | rols-PI
P1496S,P1395S
In rolsT59 homozygous embryos the developing body wall muscles exhibit a near complete block of myoblast fusion. An identical phenotype is seen in rolsT59/Df(3L)vin4 embryos.