FB2024_03 , released June 25, 2024
Allele: Dmel\mus301ZIII-2255
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General Information
Symbol
Dmel\mus301ZIII-2255
Species
D. melanogaster
Name
FlyBase ID
FBal0154904
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description

Nucleotide substitution: T1479G.

Nucleotide substitution: G3143T.

Amino acid replacement: Y455D.

Amino acid replacement: Q811H.

Amino acid replacement: Y455D. Nucleotide substitution: G?T.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Nucleotide change:

T8139315G

Amino acid change:

Y455D | mus301-PA

Reported amino acid change:

G?T

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change. Author report of nucleotide substitution likely a mis-statement. (GAC to TAC should be TAC to GAC). Author report of amino acid substitution is correct.

Nucleotide change:

G8140979T

Reported nucleotide change:

G3143T

Amino acid change:

Q811H | mus301-PA

Reported amino acid change:

Q811H

Nucleotide change:

T8139315G

Reported nucleotide change:

T1479G

Amino acid change:

Y455D | mus301-PA

Reported amino acid change:

Y455D

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Mutant larvae are sensitive to nitrogen mustard and to methyl methanesulfonate (compared to control larvae).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
mus301ZIII-2255
Name Synonyms
Secondary FlyBase IDs
    References (2)