Insertion of a 412 element in exon 6, just downstream of the sequence coding for chitin binding domain 7 in Tequila isoforms 2 and 3. This results in RNAs that are not full length and which correspond to a hybrid of Tequila and 412 sequences and which lack the serine protease domain of Tequila. EST GH28017 represents an example of this hybrid sequence.
Mutation in sequenced strain: insertion of a 412 transposon (see FBrf0180344).
The survival of TequilaIso1 mutants is not affected by infection with Gram negative or Gram positive bacteria, or the filamentous fungus B.bassiana.
The TequilaIso1 mutation is present in the Iso1 strain used in the genome sequencing project.