Amino acid replacement: L173F.
C24164690T
L173F | Apc2-PA; L153F | Apc2-PB; L173F | Apc2-PC
L173F
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
The cuticles of average maternal/zygotic Apc2e90 embryos raised at 270C show head defects, are 70% of typical wild-type length and contain denticle bands that are represented by at least one patch of denticles. This cuticle phenotype is less severe when embryos are raised at 180C.
Apc2 alleles can be divided into three categories based on their embryonic cuticle phenotypes, from weak to moderate to strong: Apc2e90 = Apc2b5 = Apc2N175K < Apc2c9 = Apc2ΔS = Apc2d40 < Apc2g41 = Apc2f90 = Apc2g10.