FB2024_03 , released June 25, 2024
Allele: Dmel\atl+t13
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General Information
Symbol
Dmel\atl+t13
Species
D. melanogaster
Name
FlyBase ID
FBal0241127
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Nature of the Allele
Progenitor genotype
Carried in construct
Cytology
Description

13kb XbaI-NotI genomic fragment containing the atl and Wsck transcription units.

Allele components
Component
Use(s)
Regulatory region(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Linked to:
XbaI-NotI restriction fragment
Comment:

The rescue fragment contains both the atl and Wsck transcription units.

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Rescues
Partially rescues

atl+t13 partially rescues atl1

Comments

atl+t13 rescues the increased number of boutons/muscle area seen at the neuromuscular junction in atl2 homozygous larvae.

atl+t13 completely rescues the bang sensitive paralysis phenotype of atl1 flies, and partially rescues their climbing ability after vortexing. atl+t13 also rescues the loss of dopaminergic neurons that is seen in atl1 flies as they age.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
atl+t13
Name Synonyms
Secondary FlyBase IDs
    References (2)