FB2024_03 , released June 25, 2024
Allele: Scer\GAL4GMR71D08
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General Information
Symbol
Scer\GAL4GMR71D08
Species
S. cerevisiae
Name
FlyBase ID
FBal0254438
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR71D08-GAL4}
Also Known As
R71D08-Gal4, R71D08
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pfeiffer et al., 2011.2.9)
Progenitor genotype
Carried in construct
P{GMR71D08-GAL4}
Cytology
Description

A 3231 base pair fragment from the flanking non-coding or intronic region of dally is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Allele components
Component
Use(s)
Regulatory region(s)
GMR71D08
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      mushroom body vertical lobe arborizing neuron 2 | subset
      (Séjourné et al., 2011)
      mushroom body output neuron 19
      (Aso et al., 2014)
      mushroom body vertical lobe arborizing neuron 2
      (Perisse et al., 2016)
      Additional Information
      Statement
      Reference

      ScerGAL4GMR71D08 labels a subset of mushroom body ventral lobe arborizing neurons 2.

      (Séjourné et al., 2011)
       
      Marker for
      mushroom body vertical lobe arborizing neuron 2
      (Perisse et al., 2016)
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using shi1.UAS at 32[o]C) of Scer\GAL4GMR71D08 cells in adults does not affect startle-induced climbing behavior, compared to controls.

      Thermogenetic activation (using TrpA1UAS.(B).cKa at 32[o]C) of Scer\GAL4GMR71D08 cells in adults significantly reduces startle-induced climbing behavior, compared to controls.

      (Sun et al., 2018)

      Inhibition (using shi1.UAS at 33[o]C) of Scer\GAL4GMR71D08 cells in adults significantly reduces short term (5 min) aversive olfactory memory, including its anaesthesia-resistant component, compared to controls; inhibition during testing significantly reduces medium term (3 h) aversive olfactory memory, but not its anaesthesia-resistant component, compared to controls, with no effect on long term (24 h after massed training) memory.

      (Bouzaiane et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR71D08
      Name Synonyms
      Secondary FlyBase IDs
        References (15)