FB2024_03 , released June 25, 2024
Allele: Ecol\lacZNdg.PP
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General Information
Symbol
Ecol\lacZNdg.PP
Species
E. coli
Name
FlyBase ID
FBal0267160
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{Ndg-lacZ.P}
Also Known As
NdgWT-lacZ, Ndg-lacZ
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Philippakis et al., 2006)
Progenitor genotype
Carried in construct
P{Ndg-lacZ.P}
Cytology
Description

A predicted enhancer from the Ndg gene is fused upstream of a nuclear localized lacZ.

(Philippakis et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
Ndg_FCenhancer
Encoded product / tool
lacZ
Tagged with
Tag:NLS(Unk)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 11
      muscle founder cell
      (Zhu et al., 2012)
      embryonic stage 15 -- 17
      embryonic/larval midgut muscle cell
      (Zhu et al., 2012)
      Additional Information
      Statement
      Reference

      The wild-type Ndg enhancer-report construct EcollacZNdg.PP is expressed in the visceral musculature of the midgut from embryonic stage 15 onwards. It is expressed from stage 11 in somatic muscle founder cells that do not express the fusion competent cell marker lmd.

      (Zhu et al., 2012)
       
      Marker for
      Reflects expression of
      Ndg
      (Zhu et al., 2012)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ecol\lacZNdg.PP
      Name Synonyms
      Secondary FlyBase IDs
        References (5)