FB2024_03 , released June 25, 2024
Allele: Dmel\Abd-Biab-6.cocu
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General Information
Symbol
Dmel\Abd-Biab-6.cocu
Species
D. melanogaster
Name
FlyBase ID
FBal0284736
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
iab-6Δ5, iab-6cocu
Key Links
Genomic Maps

Allele class
Nature of the Allele
Allele class
Cytology
Description

Reintegration of the 19.3 kb fragment removed in Abd-Biab-5.6.CI carrying an approximately 2.9 kb internal deletion spanning Drosophila genome project release 5 coordinates 3R:12721546-12724398 .

Mutations Mapped to the Genome
Curation Data
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References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
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Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
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Disease
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Modifiers Based on Experimental Evidence ( 0 )
Disease
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Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Abd-Biab-6.cocu mutant flies show distinct morphological abnormalities in the secondary cells of the male accessory gland. The mutant cells lack the large vacuolar structures seen in wild type.

When Abd-Biab-6.cocu mutant males are crossed to wild-type females the number of eggs produced is initially comparable to controls. However, at 48 hours the number of eggs produced is decreased dramatically and the total number of eggs laid over a 10 day period is significantly lower than when females are mated with wild-type males. The proportion of progeny that eclose is similar to wild type, indicating that hatchability is not affected.

Sexual receptivity is initially repressed in mates of Abd-Biab-6.cocu males, but this effect is not maintained; as with wild type males, females that have been mated with Abd-Biab-6.cocu males are unreceptive to remating with wild type males at 24 hours, but at 4 days females are more receptive to remating. By 10 days, both groups are fully receptive.

When wild type females are first mated with a Abd-Biab-6.cocu mutant male and then allowed to mate for a second time with a wild type male, the proportion of Abd-Biab-6.cocu mutant progeny is higher than the proportion of wild type progeny seen when the female first mates with the wild type and then with the Abd-Biab-6.cocu mutant male.

Females mated to either wild type or Abd-Biab-6.cocu mutant males store comparable amounts of sperm in the seminal receptacle at both two hours and four days after mating. By 10 days the females mated to Abd-Biab-6.cocu males show a slight but significant decrease in stored sperm. The amount of sperm stored in the spermathecae is comparable to wild type at all time points.

Abd-Biab-6.Δ5 mutants show no dramatical abnormalities.

External Data
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Complementation and Rescue Data
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Mutant
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Stocks (0)
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Synonyms and Secondary IDs (4)
Reported As
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Name Synonyms
Secondary FlyBase IDs
    References (3)