Amino acid replacement: R1113X.
Nucleotide substitution: C?T.
The droshaR1113X allele carries a C to T base pair change, creating a premature stop codon after the second RNase III domain.
C7935910T
C?T
R1113term | drosha-PA
R1113term
droshaR1113X/Df(2R)Exel6055 transheterozygous animals die as tanned larvae with rudimentary imaginal discs.
Homozygous clones of early larval born anterodorsal projection neurons (adPNs) in the adult brain appear grossly normal.