FlyBase Allele Report: Dmel\mip130[1-723+1-36]

General Information

Symbol

Dmel\mip130^1-723+1-36

Species

D. melanogaster

Name

FlyBase ID

FBal0304386

Feature type

allele

Associated gene

Dmel\mip130

Associated Insertion(s)

TI{TI}mip130^1-723+1-36

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

FLPase

(Beall et al., 2004)

gene targeting by homologous recombination

(Beall et al., 2004)

I-SceI

(Beall et al., 2004)

Progenitor genotype

Associated Insertion(s)

TI{TI}mip130^1-723+1-36

Cytology

Description

Duplication at the mip130 locus. The left copy contains a new EcoRI site 2136 nucleotides from the start codon and can produce a 723 amino acid, C-terminal truncated protein. The right copy contains a new BamHI site 45 nucleotides from the start codon and can produce a 36 amino acid protein (of which the last 21 amino acids are not wild-type mip130 sequence). A single FRT site, a w[+] marker and a RS(I-CreI) site are present between the two copies.

(Beall et al., 2004)

Allele components

Component

Use(s)

Also carries

FRT

recombinase target site

RS(I-CreI)

nuclease target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased body size

(Beall et al., 2004)

female sterile

(Beall et al., 2004)

viable

(Beall et al., 2004)

Phenotype Manifest In

egg chorion

(Beall et al., 2004)

Detailed Description

Statement

Reference

Mutant animals are smaller than wild-type and are unhealthy. Mutant females produce eggs that are flaccid and have thin eggshells.

Mutant animals are smaller than wild-type and are unhealthy.

(Beall et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT suppressed by

Statement

Reference

mip130^1-723+1-36 has female sterile phenotype, non-suppressible by Myb^MH107

(Beall et al., 2004)

Suppressor of

Statement

Reference

mip130^1-723+1-36 is a suppressor of lethal | recessive phenotype of Myb^MH107

(Beall et al., 2004)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

83142

TI{TI}mip130^1-723+1-36 w^*/FM7c, P{GAL4-Kr.C}DC1, P{UAS-GFP.S65T}DC5, sn⁺

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Dp(2;2)mip130^1-723+1-36

mip130^{1-723+1-36.3'}

mip130^{1-723+1-36.5'}

mip130^1-723+1-36

(Beall et al., 2007, Beall et al., 2004)

Name Synonyms

Secondary FlyBase IDs

FBal0158948
FBal0158947
FBab0038711

References (2)

Report Sections

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