FB2024_03 , released June 25, 2024
Allele: Scer\GAL4Orcokinin.PC
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General Information
Symbol
Scer\GAL4Orcokinin.PC
Species
S. cerevisiae
Name
Orcokinin promoter construct of Chen
FlyBase ID
FBal0319132
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{Orcokinin-GAL4.C}
Also Known As
orcokinin-GAL4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Chen et al., 2015)
Progenitor genotype
Carried in construct
P{Orcokinin-GAL4.C}
Cytology
Description

Orcokinin 5' regulatory sequences from -504 to +26 relative to the transcription start site are fused upstream of GAL4.

(Chen et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
Orcokinin
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      abdominal neuron | subset
      (Chen et al., 2015)
      embryonic/larval digestive system | restricted
      (Chen et al., 2015)
      adult stage
      posterior lateral protocerebrum | restricted
      (Chen et al., 2015)
      accessory medulla | restricted
      (Chen et al., 2015)
      adult brain | restricted
      (Chen et al., 2015)
      adult ventral nerve cord cell body rind | restricted
      (Chen et al., 2015)
      enteroendocrine cell | subset
      (Chen et al., 2015)
      Additional Information
      Statement
      Reference

      ScerGAL4Orcokinin.PC drives expression in one large pair of neuronal cell bodies in the posterior lateral protocerebrum, in four pairs of neurons in the accessory medulla, in two pairs of neurons and in one unpaired neuron positioned in the adult thoracico-abdominal ganglion cell body rind. In the larva five pairs of abdominal neurons can be detected with ScerGAL4Orcokinin.PC. In addition, expression is also seen in the digestive system and in cells that are not positive for Orcokinin mRNA or protein.

      (Chen et al., 2015)
       
      Marker for
      Reflects expression of
      Orcokinin
      (Chen et al., 2015)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Activation of Scer\GAL4Orcokinin.PC-positive neurons (by the expression of TrpA1UAS.(B).cKa under the control of Scer\GAL4Orcokinin.PC) leads to decreased female fecundity.

      (Zhang et al., 2021)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scer\GAL4Orcokinin.PC
      Name Synonyms
      Orcokinin promoter construct of Chen
      Secondary FlyBase IDs
        References (4)