FB2024_02 , released April 23, 2024
Allele: Dmel\aayKG05974
Open Close
General Information
Symbol
Dmel\aayKG05974
Species
D. melanogaster
Name
FlyBase ID
FBal0341383
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Mutagen
    Nature of the Allele
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Cytology
    Description

    A P- element insertion upstream of the 5'UTR of aay that reduces aay mRNA levels to ~30%.

    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Under standard fed conditions, aayKG05974 homozygotes show a small but significant increase in sleep time, a reciprocal significant increase in sleep latency period, a significant decrease in arousability by light stimuli, and a small but significant decrease in walking activity, but no change in sleep rebound after sleep deprivation or in climbing capacity, as compared to heterozygous or wild-type controls.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    aayKG05974
    Name Synonyms
    Secondary FlyBase IDs
      References (1)