FB2024_03 , released June 25, 2024
Allele: Dmel\pebREF-WN35
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General Information
Symbol
Dmel\pebREF-WN35
Species
D. melanogaster
Name
FlyBase ID
FBal0360957
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description

Deletion at the endogenous peb locus, spanning the target sites of the two sgRNAs encoded by P{TOE.GS00052}; the deletion is upstream of the peb promoter and results in the transcription unit being refractory to overexpression mediated by P{TOE.GS00052} in combination with a source of dCas9::VPR.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Comment:

62bp deletion upstream of the peb transcription unit causing the transcription unit to be refractory to overexpression mediated by P{TOE.GS00052} in combination with a source of dCas9::VPR.

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

'peb[REF-BHR17]', 'peb[REF-WN30]', 'peb[REF-WN31]', 'peb[REF-WN35]' and 'peb[REF-WN36]' all contain an identical lesion and were isolated from the same bottle. They thus likely correspond to a 'cluster' (independent isolates of a single premeiotic mutagenic event).

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
hntREF-WN35
pebREF-WN35
Name Synonyms
Secondary FlyBase IDs
    References (1)